Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4950108 | 0.83 | ALDH1A1 (0.48) | ALDH1A1TSHRFOLH1MRGPRX4LOXL2 | |
| SCHEMBL10655399 | 0.82 | FOLH1 (0.66) | ALDH1A1FOLH1MRGPRX4KMT2A | |
| SCHEMBL30578357 | 0.82 | FOLH1 (0.66) | ALDH1A1FOLH1MRGPRX4KMT2A | |
| SCHEMBL29472003 | 0.82 | TSHR (0.47) | ALDH1A1TSHRFOLH1MRGPRX4LOXL2 | |
| SCHEMBL39676 | 0.82 | TSHR (0.47) | ALDH1A1TSHRFOLH1MRGPRX4LOXL2 | |
| SCHEMBL16240333 | 0.82 | PRSS1 (0.55) | ALDH1A1TSHRFOLH1LOXL2CYP4F2 | |
| SCHEMBL7021382 | 0.80 | PARP1 (0.57) | TSHRFOLH1MRGPRX4MEN1KMT2A | |
| SCHEMBL46611 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TSHRFOLH1MRGPRX4LOXL2 | |
| SCHEMBL7637125 | 0.80 | MAOB (0.51) | ALDH1A1MRGPRX4MEN1NPC1RAB9A | |
| SCHEMBL18412078 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TSHRFOLH1MRGPRX4LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1616384-A | Difluoroalkylaromatics | BAYER CHEMICALS AG (DE) | 2005-05-18 | — | — | CN | claimed |
| CN-117384167-A | Dihydropyrimidine [4,5-d ] pyrimidine-2 (H) -ketone Nrf2 activator and preparation method and application thereof | 寒武智元(南京)生物医药科技有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-107253943-B | Photochromic compounds and compositions | 光学转变公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-106132923-B | Oligoaniline derivative, charge-transporting varnish and organic electroluminescent device | 日产化学工业株式会社 | 2019-11-15 | — | — | CN | disclosed |
| CN-107210377-B | Varnish for forming charge-transporting thin film | 日产化学工业株式会社 | 2019-07-05 | — | — | CN | disclosed |
| CN-109923114-A | Pyrazolopyridine derivatives as HPK1 modulators and their use for the treatment of cancer | 因赛特公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-107112428-B | Charge-transporting varnish and organic electroluminescent device | 日产化学工业株式会社 | 2019-01-22 | — | — | CN | disclosed |
| CN-104640858-B | Cyclic ether pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use | 霍夫曼-拉罗奇有限公司 | 2018-11-06 | — | — | CN | disclosed |
| CN-108698982-A | FLUORINE ATOM-CONTAINING COMPOUND AND USE THEREOF | 日产化学工业株式会社 | 2018-10-23 | — | — | CN | disclosed |
| EP-2651912-B1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL INC (US) | 2018-10-03 | — | — | EP | disclosed |
| CN-102781915-A | Diacylglycerol acyltransferase inhibitors | PIRAMAL LIFE SCIENCES LTD | 2012-11-14 | — | — | CN | disclosed |
| WO-2012082506-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | WO | disclosed |
| US-20120156521-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| CN-1849307-B | Substituted 2-carbonylamino-6-piperidinaminopyridines and substituted 1-carbonylamino-3-piperidinaminobenzenes as 5-ht1f agonists | LILLY CO ELI | 2011-08-03 | — | — | CN | disclosed |
| CN-101801937-A | Quinazolinone compounds and methods of use thereof | ARQULE INC | 2010-08-11 | — | — | CN | disclosed |
| CN-100577663-C | Fused heterocyclic kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2010-01-06 | — | — | CN | disclosed |
| CN-1849307-A | As 5-HT1FSubstituted 2-carbonylamino-6-agonistsPiperidinylaminopyridines and substituted 1-carbonylamino-3-piperidinylaminophenyls | LILLY CO ELI (US) | 2006-10-18 | — | — | CN | disclosed |
| CN-1616384-A | Difluoroalkylaromatics | BAYER CHEMICALS AG (DE) | 2005-05-18 | — | — | CN | disclosed |
| CN-1019668-B | process for preparing quinolone carboxylic acid derivatives | KYORIN SEIYAKU KK (JP) | 1992-12-30 | — | — | CN | disclosed |
| CN-87101984-A | Carbostyril carboxylic acid derivatives and preparation method thereof | — | 1987-10-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120156521-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | CRY2, CRY1, PPOX | ALDH1A1 1243/4885TSHR 4783/4885FOLH1 3971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.