Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4950108 | 0.83 | ALDH1A1 (0.48) | ALDH1A1TSHRFOLH1LOXL2CYP4F2 | |
| SCHEMBL46964 | 0.82 | FOLH1 (0.66) | FOLH1MRGPRX4TP53NFKB1RAB9A | |
| SCHEMBL29472003 | 0.82 | TSHR (0.47) | ALDH1A1TSHRFOLH1LOXL2CYP4F2 | |
| SCHEMBL39676 | 0.82 | TSHR (0.47) | ALDH1A1TSHRFOLH1LOXL2CYP4F2 | |
| SCHEMBL16240333 | 0.82 | PRSS1 (0.55) | ALDH1A1TSHRFOLH1LOXL2CYP4F2 | |
| SCHEMBL40196 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TSHRFOLH1LOXL2CYP4F2 | |
| SCHEMBL9929337 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TSHRFOLH1LOXL2CYP4F2 | |
| SCHEMBL27999087 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TSHRFOLH1LOXL2CYP4F2 | |
| SCHEMBL18412078 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TSHRFOLH1LOXL2CYP4F2 | |
| SCHEMBL3890873 | 0.80 | CNR2 (0.51) | ALDH1A1TSHRFOLH1LOXL2CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006475-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-01-12 | — | — | WO | disclosed |