Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28861590 | 0.83 | SLC2A1 (0.62) | ALDH1A1GAASLC2A1 | |
| SCHEMBL2954598 | 0.82 | DHFR (0.43) | SLC2A1CYP3A4 | |
| SCHEMBL28861602 | 0.80 | KDM4E (0.51) | ALDH1A1KDM4E | |
| SCHEMBL7968435 | 0.79 | PDE2A (0.50) | PDE2AALDH1A1GAAMAPK1HTT | |
| SCHEMBL27870414 | 0.78 | PIK3CG (0.57) | HTTCYP1A2 | |
| SCHEMBL2952943 | 0.78 | MAP2K7 (0.45) | CYP3A4 | |
| SCHEMBL1966500 | 0.77 | HSP90AA1 (0.56) | EGFRKDR | |
| SCHEMBL10846727 | 0.76 | PDE2A (0.62) | PDE2AALDH1A1GAAMAPK1HTT | |
| SCHEMBL10685704 | 0.76 | PDE2A (0.50) | PDE2AALDH1A1GAAMAPK1HTT | |
| SCHEMBL2946218 | 0.75 | CHEK1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |