Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 18/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 18/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29473808 | 0.87 | EZH2 (0.45) | ROCK2ROCK1EZH2 | |
| SCHEMBL28609838 | 0.83 | EZH2 (0.48) | ROCK2ROCK1EZH2 | |
| SCHEMBL28613717 | 0.83 | SMN1; SMN2 (0.52) | EZH2 | |
| SCHEMBL29473822 | 0.83 | SMN1; SMN2 (0.52) | EZH2 | |
| SCHEMBL16935193 | 0.81 | ALDH1A1 (0.47) | EZH2 | |
| SCHEMBL28598243 | 0.80 | CCR5 (0.50) | EPHX2EZH2 | |
| SCHEMBL28601010 | 0.79 | EZH2 (0.45) | ROCK2ROCK1EZH2 | |
| SCHEMBL28598409 | 0.77 | MMP13 (0.45) | EPHX2EZH2 | |
| SCHEMBL29473806 | 0.77 | EZH2 (0.43) | ROCK2ROCK1EZH2 | |
| SCHEMBL28597396 | 0.76 | CCR5 (0.48) | EPHX2EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113045494-B | Pyridone derivative and application thereof in preparation of drugs for preventing and/or treating tuberculosis caused by mycobacterium tuberculosis | 四川大学华西医院 | 2022-04-26 | — | — | CN | disclosed |