Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20014763 | 1.00 | PIN1 (0.46) | PIN1SMAD3ALDH1A1KDM4EHPGD | |
| SCHEMBL31263051 | 0.88 | XDH (0.44) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL21175334 | 0.85 | RAB9A (0.53) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL29475141 | 0.85 | RAB9A (0.53) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL21175271 | 0.85 | RAB9A (0.53) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL25025323 | 0.85 | RAB9A (0.53) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL29475124 | 0.85 | RAB9A (0.53) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL21175333 | 0.85 | PYGL (0.39) | ALDH1A1LMNAMAPTSMN1; SMN2GLA | |
| SCHEMBL29242766 | 0.85 | PYGL (0.39) | ALDH1A1LMNAMAPTSMN1; SMN2GLA | |
| SCHEMBL25044341 | 0.81 | SMAD3 (0.51) | PIN1SMAD3ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260138998-A1 | GLP-1 RECEPTOR AGONISTS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2026-05-21 | — | — | US | disclosed |
| WO-2026097750-A1 | METHOD FOR SYNTHESIZING ARYL-SUBSTITUTED CHIRAL TETRAHYDROPYRAN RING BY MEANS OF DE-SYMMETRIZATION | 杭州澳赛诺生物科技有限公司 | 2026-05-15 | — | — | WO | disclosed |
| US-12617783-B2 | Heterocyclic GLP-1R agonists | BIOMEA FUSION, INC. (US) | 2026-05-05 | — | — | US | disclosed |
| US-20260055105-A1 | PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2026-02-26 | — | — | US | disclosed |
| US-20250304572-A1 | HETEROCYCLIC GLP-1R AGONISTS | BIOMEA FUSION, INC. | 2025-10-02 | — | — | US | disclosed |
| CN-120136870-A | GLP-1 receptor targeting compounds and uses thereof | 信达生物科技有限公司 | 2025-06-13 | — | — | CN | disclosed |
| WO-2025119206-A1 | GLP-1 RECEPTOR TARGETING COMPOUNDS AND USES THEREOF | FORTVITA BIOLOGICS INC. (KY) | 2025-06-12 | — | — | WO | disclosed |
| CN-119101040-B | Method for synthesizing aryl substituted chiral tetrahydropyran ring through desymmetrical synthesis | 杭州澳赛诺医药技术有限公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-119431365-A | Phenyl heterocyclic derivative-containing regulator and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2025-02-14 | — | — | CN | disclosed |
| WO-2025026270-A1 | BENZO NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2025-02-06 | — | — | WO | disclosed |
| CN-119101040-A | Method for synthesizing aryl substituted chiral tetrahydropyran ring through desymmetrical synthesis | 杭州澳赛诺医药技术有限公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-109790161-B | Pyrazolopyridine derivatives having GLP-1 receptor agonist action | 中外制药株式会社 | 2022-03-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304572-A1 | HETEROCYCLIC GLP-1R AGONISTS | GLP1R, GPR119, GIPR | PIN1 4624/4885SMAD3 2112/4885ALDH1A1 1711/4885 |
| US-12617783-B2 | Heterocyclic GLP-1R agonists | GLP1R, GIPR, GPR119 | PIN1 4497/4885SMAD3 519/4885ALDH1A1 2149/4885 |
| US-20260138998-A1 | GLP-1 RECEPTOR AGONISTS AND METHODS OF USE | GLP1R, GIPR, GPR119 | PIN1 4498/4885SMAD3 2550/4885ALDH1A1 2405/4885 |
| US-20260055105-A1 | PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT | GLP1R, GIPR, GPR119 | PIN1 4053/4885SMAD3 2038/4885ALDH1A1 2878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.