Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13344089 | 0.78 | KAT2B (0.48) | TSHRCYP3A4PDK1ALDH1A1MAPT | |
| SCHEMBL6830861 | 0.78 | GPR35 (0.55) | TSHRCYP3A4ALDH1A1MAPTPOLB | |
| SCHEMBL7193090 | 0.78 | TSHR (0.64) | TSHRCYP3A4PDK1ALDH1A1MAPT | |
| SCHEMBL6840900 | 0.77 | TSHR (0.56) | TSHRCYP3A4ALDH1A1MAPTPOLB | |
| Potassium Ion SCHEMBL10831637 | 0.77 | TSHR (0.42) | TSHRCYP3A4PDK1ALDH1A1MAPT | |
| SCHEMBL6902179 | 0.77 | TSHR (0.42) | TSHRCYP3A4PDK1ALDH1A1MAPT | |
| SCHEMBL29362511 | 0.77 | TDP1 (0.60) | TSHRCYP3A4PDK1ALDH1A1MAPT | |
| SCHEMBL4953327 | 0.77 | BACE1 (0.50) | TSHRCYP3A4PDK1ALDH1A1POLB | |
| SCHEMBL310839 | 0.77 | TDP1 (0.60) | TSHRCYP3A4PDK1ALDH1A1MAPT | |
| SCHEMBL2949639 | 0.77 | TSHR (0.60) | TSHRPDK1ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445734-B2 | Photolabile protective groups for improved processes to prepare oligonucleotide arrays | NIGU CHEMIE GMBH (DE) | 2013-05-21 | — | — | US | disclosed |
| US-20100292458-A1 | NOVEL PHOTOLABILE PROTECTIVE GROUPS FOR IMPROVED PROCESSES TO PREPARE OLIGONUCLEOTIDE ARRAYS | NIGU CHEMIE GMBH (DE) | 2010-11-18 | — | — | US | disclosed |
| US-7759513-B2 | Photolabile protective groups for improved processes to prepare oligonucleotide arrays | NIGU CHEMIE GMBH (DE) | 2010-07-20 | — | — | US | disclosed |
| US-20040175741-A1 | Novel photolabile protective groups for improved processes to prepare oligonucleotide arrays | NIGU CHEMIE GMBH (DE) | 2004-09-09 | — | — | US | disclosed |
| WO-2004074300-A2 | NOVEL PHOTOLABILE PROTECTIVE GROUPS FOR IMPROVED PROCESSES TO PREPARE OLIGONUCLEOTIDE ARRAYS | NIGU CHEMIE GMBH (DE) | 2004-09-02 | — | — | WO | disclosed |
| US-6750335-B2 | NUCLEOSIDE FOR USE IN THE GENERATION OF PREFERENTIAL OLIGONUCEOTIDES | NIGU CHEMIE GMBH (DE) | 2004-06-15 | — | — | US | disclosed |
| EP-1224198-B1 | NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTING GROUPS | NIGU CHEMIE GMBH (DE) | 2003-04-23 | — | — | EP | disclosed |
| US-20020146737-A1 | Nucleoside derivatives with photolabile protective groups | NIGU CHEMIE GMBH (DE) | 2002-10-10 | — | — | US | disclosed |
| EP-1224198-A1 | NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTING GROUPS | NIGU CHEMIE GMBH (DE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001032671-A1 | NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTING GROUPS | NIGU CHEMIE GMBH (DE) | 2001-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292458-A1 | NOVEL PHOTOLABILE PROTECTIVE GROUPS FOR IMPROVED PROCESSES TO PREPARE OLIGONUCLEOTIDE ARRAYS | NT5C3B, NSUN2, ERCC4 | TSHR 3311/4885CYP3A4 2086/4885PDK1 4013/4885 |
| US-20040175741-A1 | Novel photolabile protective groups for improved processes to prepare oligonucleotide arrays | NT5C3B, NSUN2, DCLRE1B | TSHR 3296/4885CYP3A4 2112/4885PDK1 3890/4885 |
| US-20020146737-A1 | Nucleoside derivatives with photolabile protective groups | XRN2, XPA, NSUN2 | TSHR 1680/4885CYP3A4 3446/4885PDK1 4555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.