Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811822 | 0.86 | ALDH1A1 (0.45) | NR4A1GAAMAPTTHRBRECQL | |
| SCHEMBL2267169 | 0.85 | NPY5R (0.44) | MAPTL3MBTL1MEN1KMT2AHTT | |
| SCHEMBL1625466 | 0.80 | CDK1 (0.39) | NR4A1 | |
| SCHEMBL20703961 | 0.77 | APP (0.56) | GAAMAPTRAB9AL3MBTL1NPC1 | |
| SCHEMBL7012481 | 0.76 | EGFR (0.36) | MEN1KMT2ANPY5RDHFRTYMS | |
| SCHEMBL29378197 | 0.75 | SIRT2 (0.41) | RAB9AKDM4ETDP1NPC1MAPK1 | |
| SCHEMBL95212 | 0.75 | SIRT2 (0.41) | RAB9AKDM4ETDP1NPC1MAPK1 | |
| SCHEMBL9794374 | 0.75 | GAA (0.53) | GAAMAPTRAB9AL3MBTL1KDM4E | |
| SCHEMBL29384795 | 0.74 | RAB9A (0.61) | NR4A1GAAMAPTRAB9AL3MBTL1 | |
| SCHEMBL35262 | 0.74 | RAB9A (0.61) | NR4A1GAAMAPTRAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1728499-B1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolone derivative and a 2,3-diaminopyridine coupler | OREAL (FR) | 2010-01-06 | — | — | EP | claimed |
| EP-1728499-A1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolone derivative and a 2,3-diaminopyridine coupler | L'OREAL (FR) | 2006-12-06 | — | — | EP | claimed |
| US-6733539-B2 | HAIR DYES | L'OREAL S.A. (FR) | 2004-05-11 | — | — | US | claimed |
| US-20020170122-A9 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one enzymatic oxidizing agent, and dyeing methods | L'OREAL S.A. (FR) | 2002-11-21 | — | — | US | claimed |
| US-20020013973-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one enzymatic oxidizing agent, and dyeing methods | PLOS GREGORY (FR) | 2002-02-07 | — | — | US | claimed |
| EP-1138318-A2 | Composition for oxidative dyeing of keratinous fibres and dyeing process using same | L'OREAL (FR) | 2001-10-04 | — | — | EP | claimed |
| US-6733539-B2 | HAIR DYES | L'OREAL S.A. (FR) | 2004-05-11 | — | — | US | disclosed |
| US-20020170122-A9 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one enzymatic oxidizing agent, and dyeing methods | L'OREAL S.A. (FR) | 2002-11-21 | — | — | US | disclosed |
| US-20020013973-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one enzymatic oxidizing agent, and dyeing methods | PLOS GREGORY (FR) | 2002-02-07 | — | — | US | disclosed |
| EP-1138318-A2 | Composition for oxidative dyeing of keratinous fibres and dyeing process using same | L'OREAL (FR) | 2001-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013973-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one enzymatic oxidizing agent, and dyeing methods | KRT18, PPOX, AOX1 | NR4A1 2955/4885GAA 1324/4885MAPT 856/4885 |
| US-20020170122-A9 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one enzymatic oxidizing agent, and dyeing methods | KRT18, PPOX, AOX1 | NR4A1 2955/4885GAA 1324/4885MAPT 856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.