SCHEMBL95212

SCHEMBL95212

CNc1nc(OC)ccc1N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.41
SIRT1 Q96EB6 1/20 0.41
PDE10A Q9Y233 2/20 0.38
NNMT P40261 2/20 0.37
TDP1 Q9NUW8 3/20 0.34
POLB P06746 1/20 0.34
ALDH1A1 P00352 4/20 0.34
CYP1A2 P05177 2/20 0.34
CYP3A4 P08684 2/20 0.34
TSHR P16473 2/20 0.34
HSD17B10 Q99714 2/20 0.34
LMNA P02545 2/20 0.34
CYP2C19 P33261 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP2D6 P10635 1/20 0.34
MAPK1 P28482 1/20 0.34
SYK P43405 1/20 0.34
PTPN1 P18031 1/20 0.33
PGK1 P00558 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29378197 1.00 SIRT2 (0.41) SIRT2SIRT1PDE10ANNMTTDP1
Hydrochloric Acid SCHEMBL31409347 0.98 SIRT2 (0.40) SIRT2SIRT1PDE10ANNMTTDP1
Hydrochloric Acid SCHEMBL3391003 0.98 SIRT2 (0.40) SIRT2SIRT1PDE10ANNMTTDP1
Hydrochloric Acid SCHEMBL4602018 0.98 SIRT2 (0.40) SIRT2SIRT1PDE10ANNMTTDP1
Hydrochloric Acid SCHEMBL22612465 0.96 SIRT2 (0.39) SIRT2SIRT1PDE10ANNMTTDP1
Sulfuric Acid SCHEMBL8448369 0.90 NNMT (0.38) SIRT2SIRT1PDE10ANNMTTDP1
Orcinol SCHEMBL6424543 0.86 NNMT (0.36) SIRT2SIRT1PDE10ANNMTTDP1
Resorcinol SCHEMBL8056965 0.86 HSD17B1 (0.41) SIRT2SIRT1NNMTTDP1ALDH1A1
SCHEMBL8043904 0.84 NNMT (0.35) SIRT2SIRT1PDE10ANNMTALDH1A1
SCHEMBL3245424 0.83 ALDH1A1 (0.41) SIRT2SIRT1PDE10ANNMTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5347 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144724-A1 Mixture of at least five surfactants (I1) to (I5) WELLA GERMANY GMBH (DE) 2026-05-28 US claimed
US-12636241-B1 Method and composition for oxidative hair coloring WELLA OPERATIONS US LLC (US) 2026-05-26 US claimed
US-12622856-B2 Agent for oxidative dyeing of keratin fibers, containing isatin and at least one defined polymer HENKEL AG & CO. KGAA (DE) 2026-05-12 US claimed
US-12564545-B2 Hair coloring compositions comprising 2-amino-1-propanol as alkalising agents WELLA GERMANY GMBH (DE) 2026-03-03 US claimed
EP-4452203-B1 PROCESS FOR DYEING KERATIN FIBRES USING A COSMETIC COMPOSITION COMPRISING PROPANE-1,3-DIOL AND A DYEING COMPOSITION OREAL (FR) 2025-12-24 EP claimed
US-12383482-B2 Hair coloring compositions WELLA GERMANY GMBH (DE) 2025-08-12 US claimed
EP-4552630-A1 RESORCINOL FREE PERMANENT HAIR COLOR COMPOSITION AND METHOD Wella Operations US, LLC (US) 2025-05-14 EP claimed
WO-2025061319-A2 IMPROVING THE WASHING FASTNESS OF LEVEL 2 COLORATIONS BY MEANS OF A SEALING PROCESS USING SILANES HENKEL AG & CO. KGAA (DE) 2025-03-27 WO claimed
US-20250082555-A1 PROCESS FOR DYEING KERATIN FIBRES USING A COSMETIC COMPOSITION COMPRISING PROPANE-1,3-DIOL AND A DYEING COMPOSITION L'OREAL (FR) 2025-03-13 US claimed
EP-4496556-A1 AGENT FOR OXIDATIVELY DYEING KERATIN FIBERS, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE DEVELOPER TYPE, AT LEAST ONE OXIDATION DYE PRECURSOR OF THE COUPLER TYPE AND ISATIN Henkel AG & Co. KGaA (DE) 2025-01-29 EP claimed
EP-0542129-B1 Hair dye composition GOLDWELL GMBH (DE) 1995-06-14 EP claimed
US-5421833-A 2-(2'-hydroxyethylamino0-5-aminotoluene and salts as developer and hydroxy compound as coupling agent mixable with peroxide compound immediately before use GOLDWELL AG (DE) 1995-06-06 US claimed
EP-0583300-B1 HAIR COLOURING AGENT. HENKEL KGAA (DE) 1994-12-21 EP claimed
EP-0615743-A1 Hair dyeing composition GOLDWELL GmbH (DE) 1994-09-21 EP claimed
US-5318599-A Triaminohydroxypyrimidine and/or diaminodihydroxypyrimidine; 3 -amino-2-methylamino-6-methoxypyridine; natural-looking color GOLDWELL AG (DE) 1994-06-07 US claimed
EP-0583300-A1 HAIR COLOURING AGENT Henkel Kommanditgesellschaft auf Aktien (DE) 1994-02-23 EP claimed
EP-0542129-A1 Hair dye composition GOLDWELL GmbH (DE) 1993-05-19 EP claimed
US-5180399-A Kits for dyeing hair L'OREAL (FR) 1993-01-19 US claimed
WO-1992019220-A1 HAIR COLOURING AGENT HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1992-11-12 WO claimed
US-4745652-A DEVELOPERS FOR DYES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1988-05-24 US claimed