SCHEMBL29476521

SCHEMBL29476521

CC(C)[C@@H](NC(=O)[C@@H](N)CS)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 11/20 0.47
▸ FNTB P49356 11/20 0.47
▸ PGGT1B P53609 2/20 0.41
▸ BACE1 P56817 1/20 0.37
▸ ACE P12821 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29559148 0.93 FNTA (0.40) FNTAFNTBPGGT1BACE
SCHEMBL1984002 0.91 FNTA (0.39) FNTAFNTBPGGT1BACE
SCHEMBL1984006 0.91 FNTA (0.39) FNTAFNTBPGGT1BACE
SCHEMBL29615161 0.91 ENPEP (0.41) FNTAFNTBACE
SCHEMBL28101251 0.89 BACE1 (0.42) BACE1
SCHEMBL29476103 0.89 FNTA (0.40) FNTAFNTBPGGT1BACE
SCHEMBL29615112 0.89 FNTA (0.40) FNTAFNTBPGGT1BACE
SCHEMBL29511053 0.89 FNTA (0.40) FNTAFNTBPGGT1BACE
SCHEMBL30974548 0.89 BACE1 (0.35) FNTAFNTBBACE1ACE
SCHEMBL29749072 0.89 FNTA (0.38) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271400-A Peptide composition 节奏制药公司 2024-07-02 — — CN claimed
CN-118240012-A Peptide composition 节奏制药公司 2024-06-25 — — CN claimed
US-20260085092-A1 MELANOCORTIN RECEPTOR LIGANDS IPSEN PHARMA SAS (FR) 2026-03-26 — — US disclosed
US-20260053885-A1 PHARMACEUTICAL COMPOSITIONS RHYTHM PHARMACEUTICALS INC (US) 2026-02-26 — — US disclosed
US-12285460-B2 Pharmaceutical compositions RHYTHM PHARMACEUTICALS, INC. (US) 2025-04-29 — — US disclosed
CN-105492456-B Peptide composition 节奏制药公司 2024-11-01 — — CN disclosed
CN-118271400-A Peptide composition 节奏制药公司 2024-07-02 — — CN disclosed
CN-118240012-A Peptide composition 节奏制药公司 2024-06-25 — — CN disclosed
EP-4216979-A1 METHODS OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISORDERS Rhythm Pharmaceuticals, Inc. (US) 2023-08-02 — — EP disclosed
CN-116507353-A Methods of treating melanocortin-4 receptor pathway-related disorders 节奏制药公司 2023-07-28 — — CN disclosed
CN-115957297-A Pharmaceutical composition 节奏制药公司 2023-04-14 — — CN disclosed
CN-115957296-A Pharmaceutical composition 节奏制药公司 2023-04-14 — — CN disclosed
US-20220339239-A1 USE OF MELANOCORTINS TO TREAT INSULIN SENSITIVITY IPSEN PHARMA SAS (FR) 2022-10-27 — — US disclosed
US-20220160818-A1 PHARMACEUTICAL COMPOSITIONS RHYTHM PHARMACEUTICALS, INC. 2022-05-26 — — US disclosed
US-20220127305-A1 MELANOCORTIN RECEPTOR LIGANDS IPSEN PHARMA SAS (FR) 2022-04-28 — — US disclosed
WO-2022067086-A1 METHODS OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISORDERS RHYTHM PHARMACEUTICALS, INC. (US) 2022-03-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220160818-A1 PHARMACEUTICAL COMPOSITIONS PCTP, SLC27A1, CETP FNTA 716/4885FNTB 2340/4885PGGT1B 901/4885
US-20260085092-A1 MELANOCORTIN RECEPTOR LIGANDS THRB, MC1R, MC5R FNTA 4436/4885FNTB 1883/4885PGGT1B 1420/4885
US-12285460-B2 Pharmaceutical compositions PCTP, SLC27A1, CETP FNTA 716/4885FNTB 2340/4885PGGT1B 901/4885
US-20220339239-A1 USE OF MELANOCORTINS TO TREAT INSULIN SENSITIVITY MC4R, MC1R, MC3R FNTA 3268/4885FNTB 3846/4885PGGT1B 4041/4885
US-20220127305-A1 MELANOCORTIN RECEPTOR LIGANDS MC3R, MC1R, MC5R FNTA 2986/4885FNTB 3953/4885PGGT1B 2940/4885
US-20260053885-A1 PHARMACEUTICAL COMPOSITIONS ARGLU1, FFAR3, ASNS FNTA 1357/4885FNTB 2887/4885PGGT1B 583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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