Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 7/20 | 0.54 |
| ▸ | PRMT5 | O14744 | 8/20 | 0.51 |
| ▸ | METTL3 | Q86U44 | 9/20 | 0.49 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29478310 | 0.90 | ADK (0.51) | ADKPRMT5METTL3DOT1L | |
| SCHEMBL24313824 | 0.84 | ADK (0.48) | ADKPRMT5METTL3DOT1L | |
| SCHEMBL29611067 | 0.84 | ADK (0.48) | ADKPRMT5METTL3DOT1L | |
| SCHEMBL29478319 | 0.83 | ADK (0.47) | ADKPRMT5METTL3 | |
| SCHEMBL29478317 | 0.83 | ADK (0.47) | ADKPRMT5METTL3 | |
| SCHEMBL19590291 | 0.82 | ADORA3 (0.58) | DOT1LALDH1A1 | |
| SCHEMBL25389125 | 0.82 | ADORA3 (0.58) | DOT1LALDH1A1 | |
| SCHEMBL29973013 | 0.82 | ADORA3 (0.58) | DOT1LALDH1A1 | |
| SCHEMBL24377184 | 0.82 | ADORA3 (0.58) | DOT1LALDH1A1 | |
| SCHEMBL24293493 | 0.81 | ADK (0.67) | ADKPRMT5METTL3DOT1LNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022074391-A1 | COMPOUNDS INHIBITORS OF METTL3 | STORM THERAPEUTICS LIMITED (GB) | 2022-04-14 | — | — | WO | disclosed |