SCHEMBL2948065

SCHEMBL2948065

CCN(O)c1ccc(C)cc1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.46
TP53 P04637 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
LMNA P02545 2/20 0.39
CHRM1 P11229 1/20 0.39
SLC6A2 P23975 1/20 0.39
ADRA1A P35348 1/20 0.39
HTR2B P41595 1/20 0.39
ALOX15 P16050 2/20 0.38
HSD17B10 Q99714 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.36
HPGD P15428 2/20 0.36
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36
ALOX12 P18054 1/20 0.36
KMT2A Q03164 1/20 0.36
AMY1A P0DUB6 1/20 0.36
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14524368 0.82 TRPA1 (0.48) TRPA1TP53TDP1LMNACHRM1
SCHEMBL23864872 0.82 TDP1 (0.41) TP53TDP1LMNAALDH1A1MAPT
SCHEMBL124063 0.78 ALDH1A1 (0.45) TP53TDP1SLC6A2ALOX15HSD17B10
SCHEMBL7634615 0.78 HPGD (0.36) TP53TDP1ALDH1A1MAPTHPGD
SCHEMBL1246815 0.74 ALDH1A1 (0.35) TP53TDP1LMNAALOX15HSD17B10
SCHEMBL12401692 0.74 TRPA1 (0.54) TRPA1TP53TDP1LMNACHRM1
SCHEMBL2204568 0.72 LMNA (0.39) TP53TDP1LMNAALOX15HSD17B10
SCHEMBL6515925 0.72 CYP3A4 (0.41) CHRM1ADRA1AHTR2BALOX15ALDH1A1
SCHEMBL28361701 0.72 LMNA (0.48) TRPA1TP53TDP1LMNACHRM1
SCHEMBL29085133 0.72 CSNK2A1 (0.40) TRPA1TP53TDP1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11285094-B2 Nail coating compositions and methods having powdered activator HAILE DANNY LEE (US) 2022-03-29 US claimed
US-20200030221-A1 NAIL COATING COMPOSITIONS AND METHODS HAVING POWDERED ACTIVATOR HAILE DANNY LEE (US) 2020-01-30 US claimed
CN-110527079-A Add the flame retardant polyether polyol and preparation method thereof of hydramine WUHAN INST TECHNOLOGY 2019-12-03 CN claimed
EP-2912131-B1 ADHESIVE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2018-06-06 EP claimed
US-9657203-B2 Adhesive compositions Henkel IP & Holding GmbH (DE) 2017-05-23 US claimed
US-9574118-B2 Adhesive compositions Henkel IP & Holding GmbH (DE) 2017-02-21 US claimed
US-20150225626-A1 ADHESIVE COMPOSITIONS HENKEL AG & CO. KGAA (DE) 2015-08-13 US claimed
US-20140235758-A1 ADHESIVE COMPOSITIONS Henkel US IP LLC (US) 2014-08-21 US claimed
WO-2013074265-A1 ADHESIVE COMPOSITIONS HENKEL CORPORATION (US) 2013-05-23 WO claimed
CN-101244013-B Nano-composite resin dental material for numerical control machine-shaping and preparation thereof UNIV SOUTH CHINA TECH 2010-04-07 CN claimed
US-20100065210-A1 FLOWABLE NON-SAGGING ADHESIVE COMPOSITIONS HENKEL CORPORATION (US) 2010-03-18 US claimed
CN-101244013-A Nano-composite resin dental material for numerical control machine-shaping and preparation thereof UNIV SOUTH CHINA TECH (CN) 2008-08-20 CN claimed
WO-2008057414-A1 FLOWABLE, NON-SAGGING ADHESIVE COMPOSITIONS HENKEL CORPORATION (US) 2008-05-15 WO claimed
CN-1291090-A Composition for making temporary crowns and bridges KERR CORP (US) 2001-04-11 CN claimed
US-4217264-A SILICA, ALUMINA, AND OXIDE OF ZIRCONIUM, HAFNIUM, TANTALUM, OR TIN AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1980-08-12 US claimed
US-20240384142-A1 (METH)ACRYLATE-BASED TOUGHENED ADHESIVES HENKEL AG & CO. KGAA (DE) 2024-11-21 US disclosed
WO-2023147115-A1 (METH)ACRYLATE-BASED TOUGHENED ADHESIVES HENKEL AG & CO. KGAA (DE) 2023-08-03 WO disclosed
US-4813875-A QUICK-SETTING FREE RADICAL POLYMERIZABLE RESIN DENTSPLY RESEARCH & DEVELOPMENT CORP. (US) 1989-03-21 US disclosed
EP-0269071-A2 Chain extended urethane diacrylate and dental impression formation DENTSPLY INTERNATIONAL, INC. (US) 1988-06-01 EP disclosed
US-4572920-A ANION EXCHANGE MONOMER, ACRYLIC MONOMER FOR PREVENTION OF DENTAL CARIES RESEARCH CORPORATION (US) 1986-02-25 US disclosed