Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.35 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2948065 | 0.74 | TRPA1 (0.46) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL27735491 | 0.73 | TTR (0.33) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13890691 | 0.72 | GABRA1 (0.41) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL16026915 | 0.71 | ALDH1A1 (0.35) | ALDH1A1MAPK1HIF1AHSD17B10TP53 | |
| SCHEMBL3316934 | 0.68 | PTGS2 (0.48) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL21087428 | 0.67 | TSHR (0.46) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL2204568 | 0.67 | LMNA (0.39) | ALDH1A1MAPTKDM4ELMNATDP1 | |
| SCHEMBL12844550 | 0.67 | PTGS1 (0.57) | ALDH1A1MAPTTP53TSHRGAA | |
| SCHEMBL9499701 | 0.67 | MEN1 (0.58) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL27311927 | 0.66 | HSD17B3 (0.38) | ALDH1A1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191683-A | Method for preparing N, N-dihydroxyethyl-4-nitrosoaniline in pipeline manner | 浙江鼎龙科技有限公司 | 2018-06-22 | — | — | CN | claimed |
| CN-108191683-A | Method for preparing N, N-dihydroxyethyl-4-nitrosoaniline in pipeline manner | 浙江鼎龙科技有限公司 | 2018-06-22 | — | — | CN | disclosed |
| CN-108191683-A | Method for preparing N, N-dihydroxyethyl-4-nitrosoaniline in pipeline manner | 浙江鼎龙科技有限公司 | 2018-06-22 | — | — | CN | disclosed |
| CN-102575278-B | Fructosyl peptidyl oxidase and sensor for assaying a glycated protein | HOFFMANN LA ROCHE | 2014-02-19 | — | — | CN | disclosed |
| CN-102575278-A | Fructosyl peptidyl oxidase and sensor for assaying a glycated protein | HOFFMANN LA ROCHE | 2012-07-11 | — | — | CN | disclosed |
| EP-2462223-A2 | FRUCTOSYL AMINO ACID OXIDASE | Roche Diagnostics GmbH (DE) | 2012-06-13 | — | — | EP | disclosed |
| WO-2011015326-A2 | FRUCTOSYL AMINO ACID OXIDASE | ROCHE DIAGNOSTICS GMBH (DE) | 2011-02-10 | — | — | WO | disclosed |