SCHEMBL29482125

SCHEMBL29482125

Cc1ccc(-c2nc3c(nc2-c2ccc(C)cc2)N(CCCCCCC(=O)O)CCC3)cc1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ LTB4R Q15722 1/20 0.39
▸ ALDH1A1 P00352 2/20 0.38
▸ MAPT P10636 2/20 0.38
▸ PTGIR P43119 4/20 0.37
▸ FFAR4 Q5NUL3 2/20 0.36
▸ NPC1 O15118 1/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ RXRA P19793 2/20 0.35
▸ RXRB P28702 2/20 0.35
▸ CNR1 P21554 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ GAA P10253 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ HRH3 Q9Y5N1 1/20 0.34
▸ PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL361200 1.00 LTB4R (0.39) LTB4RALDH1A1MAPTPTGIRFFAR4
SCHEMBL360807 1.00 LTB4R (0.39) LTB4RALDH1A1MAPTPTGIRFFAR4
SCHEMBL15110410 1.00 LTB4R (0.39) LTB4RALDH1A1MAPTPTGIRFFAR4
SCHEMBL15110756 1.00 LTB4R (0.39) LTB4RALDH1A1MAPTPTGIRFFAR4
Hydrochloric Acid SCHEMBL15110833 0.99 LTB4R (0.39) LTB4RALDH1A1MAPTPTGIRFFAR4
SCHEMBL363395 0.97 LTB4R (0.44) LTB4RALDH1A1MAPTPTGIRRXRA
SCHEMBL361581 0.97 LTB4R (0.44) LTB4RALDH1A1MAPTPTGIRRXRA
Sulfuric Acid SCHEMBL15110406 0.96 LTB4R (0.37) LTB4RALDH1A1MAPTPTGIRFFAR4
SCHEMBL15110851 0.95 ALDH1A1 (0.39) LTB4RALDH1A1MAPTPTGIRGAA
SCHEMBL15111305 0.95 PKM (0.41) LTB4RALDH1A1MAPTPTGIRFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4620525-A2 METHODS AND COMPOSITIONS FOR TREATMENT OF PULMONARY HYPERTENSION AND OTHER LUNG DISORDERS Respira Therapeutics, Inc. (US) 2025-09-24 — — EP disclosed
US-20250195855-A1 INGESTIBLE DEVICE FOR DELIVERY OF THERAPEUTIC AGENT TO THE GASTROINTESTINAL TRACT GLAS USA LLC 2025-06-19 — — US disclosed
US-20250195531-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF PULMONARY HYPERTENSION AND OTHER LUNG DISORDERS Respira Therapeutics, Inc. (US) 2025-06-19 — — US disclosed
US-12263174-B2 Methods and compositions for treatment of pulmonary hypertension and other lung disorders Respira Therapeutics, Inc. (US) 2025-04-01 — — US disclosed
EP-4493258-A1 INGESTIBLE DEVICE FOR DELIVERY OF THERAPEUTIC AGENT TO THE GASTROINTESTINAL TRACT Biora Therapeutics, Inc. (US) 2025-01-22 — — EP disclosed
CN-119173296-A Ingestible devices for delivering therapeutic agents to the gastrointestinal tract 比奥拉治疗股份有限公司 2024-12-20 — — CN disclosed
EP-3870261-B1 INGESTIBLE DEVICE FOR DELIVERY OF THERAPEUTIC AGENT TO THE GASTROINTESTINAL TRACT BIORA THERAPEUTICS INC (US) 2024-01-31 — — EP disclosed
EP-4309722-A2 INGESTIBLE DEVICE FOR DELIVERY OF THERAPEUTIC AGENT TO THE GASTROINTESTINAL TRACT Biora Therapeutics, Inc. (US) 2024-01-24 — — EP disclosed
WO-2023178354-A1 INGESTIBLE DEVICE FOR DELIVERY OF THERAPEUTIC AGENT TO THE GASTROINTESTINAL TRACT BIORA THERAPEUTICS, INC. (US) 2023-09-21 — — WO disclosed
US-11707610-B2 Ingestible device for delivery of therapeutic agent to the gastrointestinal tract BIORA THERAPEUTICS, INC. (US) 2023-07-25 — — US disclosed
US-20230149315-A1 INGESTIBLE DEVICE FOR DELIVERY OF THERAPEUTIC AGENT TO THE GASTROINTESTINAL TRACT GLAS USA LLC 2023-05-18 — — US disclosed
CN-115666704-A Ingestible device for delivery of therapeutic agents to the gastrointestinal tract 比奥拉治疗股份有限公司 2023-01-31 — — CN disclosed
US-11491161-B2 Methods and compositions for treatment of pulmonary hypertension and other lung disorders Respira Therapeutics, Inc. (US) 2022-11-08 — — US disclosed
US-11491160-B2 Methods and compositions for treatment of pulmonary hypertension and other lung disorders Respira Therapeutics, Inc. (US) 2022-11-08 — — US disclosed
US-20220347183-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF PULMONARY HYPERTENSION AND OTHER LUNG DISORDERS Respira Therapeutics, Inc. (US) 2022-11-03 — — US disclosed
US-20220079949-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF PULMONARY HYPERTENSION AND OTHER LUNG DISORDERS Respira Therapeutics, Inc. (US) 2022-03-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11707610-B2 Ingestible device for delivery of therapeutic agent to the gastrointestinal tract MUC1, SLC10A2, FABP2 LTB4R 304/4885ALDH1A1 2415/4885MAPT 3032/4885
US-20230149315-A1 INGESTIBLE DEVICE FOR DELIVERY OF THERAPEUTIC AGENT TO THE GASTROINTESTINAL TRACT MUC1, SLC10A2, FABP2 LTB4R 304/4885ALDH1A1 2415/4885MAPT 3032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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