Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2956345 | 0.90 | PDE4B (0.42) | PDE4BHSP90AA1HSP90AB1CCNT1CDK9 | |
| SCHEMBL2950527 | 0.85 | ADORA2A (0.42) | ADORA2AHSP90AA1HSP90AB1DRD2DRD1 | |
| SCHEMBL2946224 | 0.79 | CDK1 (0.40) | HSP90AA1HSP90AB1DRD3 | |
| SCHEMBL2946279 | 0.76 | PDE4B (0.46) | PDE4BALDH1A1LMNAPIK3CDPIK3R1 | |
| SCHEMBL2948407 | 0.75 | PIK3CD (0.40) | ALDH1A1LMNAPIK3CDPIK3R1PIK3CA | |
| SCHEMBL2946341 | 0.75 | PIK3CD (0.39) | ALDH1A1PIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL2949173 | 0.72 | HSP90AA1 (0.47) | KMT2AHSP90AA1HSP90AB1SMN1; SMN2 | |
| SCHEMBL2950550 | 0.71 | CYP1A2 (0.50) | PIK3R1PIK3CAADORA2ASMN1; SMN2 | |
| SCHEMBL2953676 | 0.71 | EGFR (0.39) | CCNT1CDK9 | |
| SCHEMBL2952077 | 0.71 | INSR (0.42) | KMT2AHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |