Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASPH | Q12797 | 3/20 | 0.44 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.38 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23012611 | 1.00 | ASPH (0.44) | ASPHAGBL2KMOKDM4EKDM8 | |
| SCHEMBL26742425 | 0.85 | AGBL2 (0.39) | AGBL2KDM4EKMT2AHPGDALDH1A1 | |
| SCHEMBL29921698 | 0.85 | KMT2A (0.51) | AGBL2KDM4EKMT2AALDH1A1CES2 | |
| SCHEMBL30595863 | 0.80 | CFTR (0.46) | KMT2AALDH1A1MEN1 | |
| SCHEMBL25226760 | 0.80 | CFTR (0.46) | KMT2AALDH1A1MEN1 | |
| SCHEMBL19268307 | 0.80 | GRN (0.42) | ASPHKDM4EALDH1A1RXRARXRB | |
| SCHEMBL17595192 | 0.77 | ALOX15 (0.54) | ASPHKMOKDM4EHPGDALDH1A1 | |
| SCHEMBL30428298 | 0.74 | AGBL2 (0.51) | AGBL2KDM4EHPGDRXRARXRB | |
| SCHEMBL17653894 | 0.74 | AGBL2 (0.51) | AGBL2KDM4EHPGDRXRARXRB | |
| SCHEMBL4430447 | 0.74 | ALDH1A1 (0.36) | AGBL2KDM4EALDH1A1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710453-A | Kinase inhibitors and uses thereof | 璧辰医药技术股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-113429440-B | Prodrug of spiro compound, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-113264945-B | Spiro derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-114206856-A | Anti-malarial hexahydropyrimidine analogues | UCB生物制药有限责任公司 | 2022-03-18 | — | — | CN | disclosed |