SCHEMBL29488448

SCHEMBL29488448

NC(=O)c1cc(C(F)(F)F)nn1-c1ncccc1Cl

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
MEN1 O00255 1/20 0.45
ALDH1A1 P00352 1/20 0.45
MAPT P10636 1/20 0.45
KMT2A Q03164 1/20 0.45
KLKB1 P03952 2/20 0.42
TRPV1 Q8NER1 5/20 0.40
TRPA1 O75762 2/20 0.40
SCN9A Q15858 3/20 0.39
PTGS1 P23219 2/20 0.39
PTGS2 P35354 2/20 0.39
NR3C2 P08235 1/20 0.39
SCN10A Q9Y5Y9 1/20 0.38
CARM1 Q86X55 1/20 0.36
OPRL1 P41146 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15272015 1.00 KDM4E (0.48) KDM4EL3MBTL1MEN1ALDH1A1MAPT
SCHEMBL535347 0.89 KLKB1 (0.49) KDM4EL3MBTL1MEN1ALDH1A1MAPT
SCHEMBL30863652 0.89 KDM4E (0.49) KDM4EL3MBTL1MEN1ALDH1A1MAPT
SCHEMBL114535 0.89 KDM4E (0.49) KDM4EL3MBTL1MEN1ALDH1A1MAPT
SCHEMBL354326 0.88 KDM4E (0.45) KDM4EL3MBTL1MEN1ALDH1A1MAPT
Hydrochloric Acid SCHEMBL536232 0.88 KLKB1 (0.48) KDM4EL3MBTL1MEN1ALDH1A1MAPT
SCHEMBL7061756 0.86 KDM4E (0.49) KDM4EL3MBTL1MEN1ALDH1A1MAPT
SCHEMBL15971608 0.82 F10 (0.39) KDM4EL3MBTL1MEN1ALDH1A1MAPT
SCHEMBL1680138 0.82 ALDH1A1 (0.44) KDM4EL3MBTL1MEN1ALDH1A1MAPT
SCHEMBL25275831 0.81 F10 (0.38) KDM4EL3MBTL1MEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023044584-A1 SYNERGISTIC PESTICIDAL COMPOSITIONS AND METHODS FOR DELIVERY OF INSECTICIDAL ACTIVE INGREDIENTS TERRAMERA, INC. (CA) 2023-03-30 WO claimed
CN-115299444-A Composition containing trifloxystrobin and application 山东省联合农药工业有限公司 2022-11-08 CN claimed
CN-115251064-A Sterilization insecticidal composition and application thereof 山东省联合农药工业有限公司 2022-11-01 CN claimed
CN-117813006-A Methods for controlling diamide-resistant pests and compounds thereof 先正达农作物保护股份公司 2024-04-02 CN disclosed
CN-117794908-A (3-quinolinyl) -quinazolines 巴斯夫欧洲公司 2024-03-29 CN disclosed
CN-117794907-A (3-pyridinyl) -quinazolines 巴斯夫欧洲公司 2024-03-29 CN disclosed
CN-117355519-A Novel substituted pyridines as fungicides 巴斯夫欧洲公司 2024-01-05 CN disclosed
CN-117355518-A Novel substituted pyridines as fungicides 巴斯夫欧洲公司 2024-01-05 CN disclosed
CN-117295399-A Novel microparticles containing active substances 巴斯夫欧洲公司 2023-12-26 CN disclosed
CN-117241879-A Novel microcapsules containing active substances 巴斯夫欧洲公司 2023-12-15 CN disclosed
CN-110506038-B Pesticidal compounds 巴斯夫欧洲公司 2023-11-24 CN disclosed
CN-111683528-B Use of pyrazolidinopropyl ethers as nitrification inhibitors 巴斯夫欧洲公司 2022-12-13 CN disclosed
CN-115299444-A Composition containing trifloxystrobin and application 山东省联合农药工业有限公司 2022-11-08 CN disclosed
CN-115251064-A Sterilization insecticidal composition and application thereof 山东省联合农药工业有限公司 2022-11-01 CN disclosed
CN-111683529-B Use of alkoxypyrazoles as nitrification inhibitors 巴斯夫欧洲公司 2022-10-14 CN disclosed
US-20220295785-A1 SHEAR STABLE COMPOSITION FOR SPRAY DRIFT CONTROL BASF SE (DE) 2022-09-22 US disclosed
CN-111526719-B Silylethynyl heteroaryl compounds as nitrification inhibitors 巴斯夫欧洲公司 2022-08-16 CN disclosed
CN-108026066-B Pyridine compounds useful for combating phytopathogenic fungi 巴斯夫欧洲公司 2022-05-31 CN disclosed
CN-109068655-B Pesticidal active mixtures of tioxazafen 巴斯夫欧洲公司 2022-05-03 CN disclosed
CN-107580592-B Thioether compounds as nitrification inhibitors 巴斯夫欧洲公司 2022-03-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220295785-A1 SHEAR STABLE COMPOSITION FOR SPRAY DRIFT CONTROL PLD1, PFN1, SPIN1 KDM4E 3957/4885L3MBTL1 2750/4885MEN1 941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.