Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.32 |
| ▸ | RRM1 | P23921 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23943725 | 0.92 | CYP2A6 (0.38) | GPR84CYP1A2ALDH1A1CYP2A6HSD17B10 | |
| SCHEMBL20956678 | 0.89 | TDP1 (0.36) | GPR84ALDH1A1CYP2A6HSD17B10HPGD | |
| SCHEMBL2949327 | 0.86 | DHFR (0.40) | GPR84CYP1A2ALDH1A1CYP2A6TDP1 | |
| SCHEMBL29176 | 0.84 | MAPT (0.39) | CYP1A2ALDH1A1CYP2A6HSD17B10HPGD | |
| SCHEMBL29361524 | 0.84 | MAPT (0.39) | CYP1A2ALDH1A1CYP2A6HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL5566890 | 0.83 | DHFR (0.38) | GPR84CYP1A2ALDH1A1CYP2A6TDP1 | |
| SCHEMBL9116348 | 0.81 | MAPT (0.37) | GPR84CYP1A2ALDH1A1CYP2A6HSD17B10 | |
| Bromide SCHEMBL7948384 | 0.81 | MAPT (0.37) | CYP1A2ALDH1A1CYP2A6HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL7937215 | 0.81 | RAB9A (0.40) | CYP1A2ALDH1A1CYP2A6HSD17B10HPGD | |
| Bromide SCHEMBL7948386 | 0.81 | MAPT (0.37) | CYP1A2ALDH1A1CYP2A6HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323970-A1 | METHOD FOR PRODUCING A SPIROOXINDOLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2021-10-21 | — | — | US | disclosed |
| US-9376447-B2 | Transfer hydrogenation of cyclopamine analogs | INFINITY PHARMACEUTICALS, INC. (US) | 2016-06-28 | — | — | US | disclosed |
| US-9376447-B2 | Transfer hydrogenation of cyclopamine analogs | INFINITY PHARMACEUTICALS, INC. (US) | 2016-06-28 | — | — | US | disclosed |
| US-20120065400-A1 | Transfer Hydrogenation of Cyclopamine Analogs | INFINITY PHARMACEUTICALS, INC. (US) | 2012-03-15 | — | — | US | disclosed |
| US-20120065400-A1 | Transfer Hydrogenation of Cyclopamine Analogs | INFINITY PHARMACEUTICALS, INC. (US) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065400-A1 | Transfer Hydrogenation of Cyclopamine Analogs | HVCN1, KCNQ4, KCNQ5 | GPR84 2264/4885CYP1A2 317/4885ALDH1A1 1597/4885 |
| US-20210323970-A1 | METHOD FOR PRODUCING A SPIROOXINDOLE DERIVATIVE | MDM2, TP53, RB1 | GPR84 1250/4885CYP1A2 2604/4885ALDH1A1 628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.