SCHEMBL2949574

SCHEMBL2949574

NC(=O)c1cc(Oc2ccc(N)cc2)ccc1N

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 3/20 0.59
BRAF P15056 5/20 0.53
HDAC1 Q13547 5/20 0.53
HDAC3 O15379 4/20 0.53
HDAC4 P56524 4/20 0.53
HDAC7 Q8WUI4 4/20 0.53
HDAC2 Q92769 4/20 0.53
HDAC10 Q969S8 4/20 0.53
HDAC11 Q96DB2 4/20 0.53
HDAC8 Q9BY41 4/20 0.53
HDAC6 Q9UBN7 4/20 0.53
HDAC9 Q9UKV0 4/20 0.53
HDAC5 Q9UQL6 4/20 0.53
ALDH1A1 P00352 5/20 0.50
KMT2A Q03164 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
MEN1 O00255 2/20 0.50
MAPT P10636 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
MITF O75030 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31151866 0.93 NR4A1 (0.52) PARP10BRAFHDAC1HDAC3HDAC4
SCHEMBL25328315 0.93 NR4A1 (0.52) PARP10BRAFHDAC1HDAC3HDAC4
SCHEMBL2661681 0.88 PARP10 (0.58) PARP10BRAFHDAC1HDAC3HDAC4
SCHEMBL1027446 0.86 KMT2A (0.61) PARP10BRAFHDAC1HDAC3HDAC4
SCHEMBL7767012 0.86 PARP10 (0.59) PARP10BRAFHDAC1HDAC3HDAC4
SCHEMBL7764582 0.85 MAOB (0.53) PARP10BRAFHDAC1HDAC3HDAC4
SCHEMBL31557923 0.83 PARP10 (0.56) PARP10BRAFHDAC1HDAC3HDAC4
SCHEMBL1026723 0.81 BRAF (0.56) PARP10BRAFHDAC1HDAC3HDAC4
SCHEMBL10203619 0.80 PARP10 (0.53) PARP10BRAFHDAC1HDAC3HDAC4
SCHEMBL11650147 0.80 POLB (0.59) PARP10BRAFHDAC1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5115089-A Heat resistant polymers for electrical insulation, protective coatings for electronics formed by reaction of tetracarboxylic dianhydrides and diaminoamides and diamines HITACHI CHEMICAL CO., LTD. (JP) 1992-05-19 US claimed
US-4381886-A HYDRAZIDE-IMIDE COPOLYMER HITACHI, LTD. (JP) 1983-05-03 US claimed
JP-57034524-A None JP disclosed
JP-60066438-A None JP disclosed
JP-60066437-A None JP disclosed
CN-117777581-B High temperature resistant PE packaging film 建德市广鑫塑业有限公司 2024-11-22 CN disclosed
CN-117777581-A High temperature resistant PE packaging film 建德市广鑫塑业有限公司 2024-03-29 CN disclosed
US-7751020-B2 Liquid crystal display device with two kinds of projected portions on a substrate HITACHI, LTD. (JP) 2010-07-06 US disclosed
US-7643119-B2 Liquid crystal display device having improved spacers HITACHI, LTD. (JP) 2010-01-05 US disclosed
US-20090051864-A1 Liquid crystal display device having improved spacers HITACHI, LTD. 2009-02-26 US disclosed
US-20070040984-A1 Liquid crystal display device with two kinds of projected portions on a substrate HITACHI, LTD. 2007-02-22 US disclosed
US-5194579-A Humidity and heat resistance; coatings for semiconductors, insulating films for wiring HITACHI, LTD. (JP) 1993-03-16 US disclosed
US-5115089-A Heat resistant polymers for electrical insulation, protective coatings for electronics formed by reaction of tetracarboxylic dianhydrides and diaminoamides and diamines HITACHI CHEMICAL CO., LTD. (JP) 1992-05-19 US disclosed
US-5067797-A Liquid crystal display cell and process for producing the same HITACHI, LTD. (JP) 1991-11-26 US disclosed
EP-0308270-A2 Processes for preparation of polyimide-isoindoquinazoline dione and precursor thereof Hitachi Chemical Co., Ltd. (JP) 1989-03-22 EP disclosed
JP-S6066437-A FORMING METHOD OF HEAT-RESISTANT RESIN FILM OKI ELECTRIC IND CO LTD 1985-04-16 JP disclosed
JP-S6066438-A FORMING METHOD OF HEAT-RESISTANT RESIN FILM OKI ELECTRIC IND CO LTD 1985-04-16 JP disclosed
US-4405208-A MOLECULAR ORIENTATION; ORGANICSILICONE POLYMERS; WEAR RESISTANCE SHARP KABUSHIKI KAISHA (JP) 1983-09-20 US disclosed
US-4381886-A HYDRAZIDE-IMIDE COPOLYMER HITACHI, LTD. (JP) 1983-05-03 US disclosed
JP-S5734524-A SUBSTRATE FOR SANDWICHING LIQUID CRYSTAL HITACHI CHEM CO LTD 1982-02-24 JP disclosed