Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4939285 | 0.81 | MAPT (0.51) | KDM4EMAPK1BCAT2HTTSMN1; SMN2 | |
| SCHEMBL94186 | 0.79 | TNF (0.43) | KDM4EMAPK1TAAR1POLBHTT | |
| SCHEMBL29634740 | 0.79 | TNF (0.43) | KDM4EMAPK1TAAR1POLBHTT | |
| Hydrochloric Acid SCHEMBL7591939 | 0.78 | TNF (0.43) | KDM4EMAPK1TAAR1POLBHTT | |
| SCHEMBL2944371 | 0.77 | NUDT1 (0.53) | MAPK1BCAT2HTTMAP4K4ALDH1A1 | |
| SCHEMBL6925243 | 0.71 | TNF (0.40) | KDM4EMAPK1TAAR1POLBHTT | |
| SCHEMBL4052723 | 0.71 | MAP4K4 (0.54) | MAPK1BCAT2HTTMAP4K4ALDH1A1 | |
| SCHEMBL6669525 | 0.69 | TNF (0.36) | KDM4EMAPK1TAAR1POLBHTT | |
| SCHEMBL11580569 | 0.68 | PKM (0.39) | MAPK1HTTLMNAGAAHPGD | |
| SCHEMBL18957388 | 0.68 | BCAT2 (0.50) | KDM4EMAPK1BCAT2HTTMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1728499-B1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolone derivative and a 2,3-diaminopyridine coupler | OREAL (FR) | 2010-01-06 | — | — | EP | claimed |
| EP-1728499-A1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolone derivative and a 2,3-diaminopyridine coupler | L'OREAL (FR) | 2006-12-06 | — | — | EP | claimed |
| EP-1728499-B1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolone derivative and a 2,3-diaminopyridine coupler | OREAL (FR) | 2010-01-06 | — | — | EP | disclosed |
| EP-1728499-A1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolone derivative and a 2,3-diaminopyridine coupler | L'OREAL (FR) | 2006-12-06 | — | — | EP | disclosed |