Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | SHMT2 | P34897 | 3/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29496133 | 0.83 | MAP3K12 (0.31) | MAP4K4 | |
| SCHEMBL22969291 | 0.83 | MAP4K4 (0.39) | MAP4K4MAOBHTR3ASHMT2PARP1 | |
| SCHEMBL29495699 | 0.83 | MAP4K4 (0.39) | MAP4K4MAOBHTR3ASHMT2PARP1 | |
| SCHEMBL29495744 | 0.73 | SHMT2 (0.44) | SHMT2SMN1; SMN2GAA | |
| SCHEMBL22969621 | 0.73 | SHMT2 (0.44) | SHMT2SMN1; SMN2GAA | |
| SCHEMBL22969277 | 0.73 | SHMT2 (0.42) | SHMT2SMN1; SMN2GAA | |
| SCHEMBL29495961 | 0.73 | SHMT2 (0.42) | SHMT2SMN1; SMN2GAA | |
| SCHEMBL29496148 | 0.73 | HTR3A (0.41) | HTR3APARP1GAA | |
| SCHEMBL29496138 | 0.71 | USP7 (0.33) | — | |
| SCHEMBL29496151 | 0.71 | PDE10A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269730-A | 5-heteroaryl-pyridin-2-amine compounds as neuropeptide FF receptor antagonists | 多曼治疗学公司 | 2022-04-01 | — | — | CN | disclosed |