Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PDE8B | O95263 | 1/20 | 0.35 |
| ▸ | USP1 | O94782 | 2/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23452615 | 0.83 | HCAR1 (0.44) | USP1HCAR1KDM4EMAPT | |
| SCHEMBL29501920 | 0.83 | HCAR1 (0.44) | USP1HCAR1KDM4EMAPT | |
| SCHEMBL1693391 | 0.82 | JAK2 (0.45) | CHEK2PRMT5HCAR1 | |
| SCHEMBL21593650 | 0.81 | PIK3CA (0.44) | USP1HCAR1 | |
| SCHEMBL21593598 | 0.81 | PIK3CA (0.44) | USP1HCAR1 | |
| SCHEMBL21593599 | 0.77 | USP1 (0.40) | USP1 | |
| SCHEMBL21593597 | 0.77 | USP1 (0.40) | USP1 | |
| SCHEMBL31285845 | 0.77 | ALDH1A1 (0.43) | ALDH1A1OPRK1MEN1KMT2ALMNA | |
| SCHEMBL6495180 | 0.76 | CCR5 (0.48) | ALDH1A1OPRK1KDM4ENPSR1 | |
| SCHEMBL6495183 | 0.76 | CCR5 (0.48) | ALDH1A1OPRK1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315834-B | Imidazolone derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-113121538-B | Furan derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-114315834-A | Imidazolidinone derivatives and their use in medicaments | 成都百裕制药股份有限公司 | 2022-04-12 | — | — | CN | disclosed |