Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CTH | P32929 | 1/20 | 0.32 |
| ▸ | CBS | P35520 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2946936 | 1.00 | EPHX2 (0.35) | EPHX2MEN1KMT2ABLMPMP22 | |
| SCHEMBL20175906 | 1.00 | EPHX2 (0.35) | EPHX2MEN1KMT2ABLMPMP22 | |
| SCHEMBL20175905 | 1.00 | EPHX2 (0.35) | EPHX2MEN1KMT2ABLMPMP22 | |
| SCHEMBL2945712 | 0.98 | ALDH1A1 (0.35) | EPHX2MEN1KMT2ABLMPMP22 | |
| SCHEMBL6663291 | 0.83 | MEN1 (0.33) | EPHX2MEN1KMT2ABLMPMP22 | |
| SCHEMBL2944390 | 0.83 | GABRP (0.37) | EPHX2MEN1KMT2ABLMPMP22 | |
| SCHEMBL21106821 | 0.83 | CES2 (0.45) | EPHX2MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL2951850 | 0.83 | GABRP (0.37) | EPHX2MEN1KMT2ABLMPMP22 | |
| SCHEMBL2943325 | 0.83 | GABRP (0.37) | EPHX2MEN1KMT2ABLMPMP22 | |
| SCHEMBL25885330 | 0.83 | CES2 (0.45) | EPHX2MEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236277-B2 | Process for producing nanoparticles | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-08-07 | — | — | US | claimed |
| US-20100008847-A1 | PROCESS FOR PRODUCING NANOPARTICLES | 3M INNOVATIVE PROPERTIES COMPANY | 2010-01-14 | — | — | US | claimed |
| EP-2104714-A1 | PROCESS FOR PRODUCING NANOPARTICLES | 3M Innovative Properties Company (US) | 2009-09-30 | — | — | EP | claimed |
| WO-2008079800-A1 | PROCESS FOR PRODUCING NANOPARTICLES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-07-03 | — | — | WO | claimed |
| US-7041721-B2 | Highly neutralized polymer golf ball compositions including oxa acids and methods of making same | ACUSHNET COMPANY (US) | 2006-05-09 | — | — | US | claimed |
| EP-0910362-B1 | OXA ACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PROD INC (US) | 2004-10-27 | — | — | EP | claimed |
| US-20030225197-A1 | Highly neutralized polymer golf ball compositions including oxa acids and methods of making same | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2003-12-04 | — | — | US | claimed |
| CN-1110302-C | Oxa acids and related compounds for treating skin conditions | AVON PROD INC (US) | 2003-06-04 | — | — | CN | claimed |
| US-6534543-B2 | Topical compositions with carboxy acid/ester, amide, or thioester/thioacid groups, with one or more of ether, amine, or sulfide groups; for example 3,6-dioxaheptanioic acid; peeling skin, softening hair | AVON PRODUCTS, INC. | 2003-03-18 | — | — | US | claimed |
| US-20020040056-A1 | Oxa acids and related compounds for treating skin conditions | AVON PRODUCTS, INC. | 2002-04-04 | — | — | US | claimed |
| JP-2000511900-A | — | — | 2000-09-12 | — | — | JP | claimed |
| US-6069169-A | OXA acids and related compounds for treating skin conditions | AVON PRODUCTS, INC. (US) | 2000-05-30 | — | — | US | claimed |
| EP-0910362-A4 | OXA ACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PROD INC (US) | 1999-12-22 | — | — | EP | claimed |
| CN-1221342-A | Oxo acids and related compounds for the treatment of skin conditions | AVON PROD INC (US) | 1999-06-30 | — | — | CN | claimed |
| EP-0910362-A1 | OXA ACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PRODUCTS, INC. (US) | 1999-04-28 | — | — | EP | claimed |
| US-5847003-A | Oxa acids and related compounds for treating skin conditions | AVON PRODUCTS, INC. (US) | 1998-12-08 | — | — | US | claimed |
| WO-1997046231-A1 | OXA ACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PRODUCTS, INC. (US) | 1997-12-11 | — | — | WO | claimed |
| US-20180140581-A1 | METABOLICALLY PROGRAMMED METAL CHELATORS AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-05-24 | — | — | US | disclosed |
| CN-1221342-A | Oxo acids and related compounds for the treatment of skin conditions | AVON PROD INC (US) | 1999-06-30 | — | — | CN | disclosed |
| US-5847003-A | Oxa acids and related compounds for treating skin conditions | AVON PRODUCTS, INC. (US) | 1998-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180140581-A1 | METABOLICALLY PROGRAMMED METAL CHELATORS AND USES THEREOF | FECH, SLC19A1, SLC40A1 | EPHX2 2750/4885MEN1 741/4885KMT2A 2059/4885 |
| US-20020040056-A1 | Oxa acids and related compounds for treating skin conditions | OXGR1, OXA1L, CXCR1 | EPHX2 797/4885MEN1 3238/4885KMT2A 3850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.