SCHEMBL29399159

SCHEMBL29399159

CC(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(N)=O)C(=O)O)C(C)C

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SIRT6 Q8N6T7 1/20 0.51
SIRT1 Q96EB6 1/20 0.51
FURIN P09958 10/20 0.49
PCSK6 P29122 1/20 0.49
SIRT5 Q9NXA8 1/20 0.47
GNPAT O15228 1/20 0.44
PRSS1 P07477 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30565184 0.92 SIRT6 (0.59) SIRT6SIRT1SIRT5GNPAT
SCHEMBL29723634 0.92 SIRT6 (0.59) SIRT6SIRT1SIRT5GNPAT
SCHEMBL29727369 0.90 FURIN (0.45) SIRT6SIRT1FURINPCSK6PRSS1
SCHEMBL30317673 0.89 SIRT5 (0.52) FURINSIRT5GNPAT
SCHEMBL30317615 0.89 SIRT5 (0.46) SIRT6SIRT1FURINPCSK6SIRT5
SCHEMBL18688864 0.88 GNPAT (0.45) SIRT6SIRT1FURINSIRT5GNPAT
SCHEMBL28574926 0.88 GNPAT (0.45) SIRT6SIRT1FURINSIRT5GNPAT
SCHEMBL30317597 0.88 GNPAT (0.59) FURINSIRT5GNPAT
SCHEMBL29371278 0.88 GNAI3 (0.44) FURINPRSS1
SCHEMBL20435368 0.86 SIRT6 (0.55) SIRT6SIRT1FURINPCSK6SIRT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250262314-A1 MULTIFUNCTIONAL ANTIBODIES SYNAFFIX B.V. (NL) 2025-08-21 US claimed
US-20250186606-A1 MODULAR LINKER COMPOUND FOR TARGET-BINDING DRUG CONJUGATES HEIDELBERG PHARMA RESEARCH GMBH (DE) 2025-06-12 US claimed
WO-2025120085-A1 MODULAR LINKER COMPOUND FOR TARGET-BINDING DRUG CONJUGATES HEIDELBERG PHARMA RESEARCH GMBH (DE) 2025-06-12 WO claimed
WO-2025103474-A1 DOUBLE-TOXIN ANTIBODY-DRUG CONJUGATE AND USE THEREOF 成都康弘生物科技有限公司 2025-05-22 WO claimed
CN-120019819-A Double toxin antibody drug conjugate and application thereof 成都康弘生物科技有限公司 2025-05-20 CN claimed
US-20250154270-A1 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES SPECIFIC FOR CD123 AND USES THEREOF PFIZER INC. (US) 2025-05-15 US claimed
US-20250067753-A1 Protein array-based in vitro transglutaminase assay platform for epitope mapping and immunogen design LIU CHEN (US) 2025-02-27 US claimed
CN-119424672-A Antibody drug conjugate and application thereof 成都康弘生物科技有限公司 2025-02-14 CN claimed
EP-4288108-A1 MULTIFUNCTIONAL ANTIBODIES Synaffix B.V. (NL) 2023-12-13 EP claimed
US-20230357417-A1 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES SPECIFIC FOR CD123 AND USES THEREOF PFIZER INC. (US) 2023-11-09 US claimed
US-20230330245-A1 ANTIBODY-EXATECAN CONJUGATES SYNAFFIX B.V. (NL) 2023-10-19 US claimed
EP-4213885-A1 ANTIBODY-EXATECAN CONJUGATES Synaffix B.V. (NL) 2023-07-26 EP claimed
US-11613581-B2 Antibodies and antibody-drug conjugates specific for CD123 and uses thereof PFIZER, INC. (US) 2023-03-28 US claimed
US-11602525-B2 Antibody-drug conjugates with high drug loading RINAT NEUROSCIENCE CORP. (US) 2023-03-14 US claimed
WO-2023021335-A2 PROTEIN ARRAY-BASED IN VITRO TRANSGLUTAMINASE ASSAY PLATFORM FOR EPITOPE MAPPING AND IMMUNOGEN DESIGN LIU CHEN (US) 2023-02-23 WO claimed
WO-2022167689-A9 MULTIFUNCTIONAL ANTIBODIES SYNAFFIX B.V. (NL) 2022-11-10 WO claimed
WO-2022167689-A1 MULTIFUNCTIONAL ANTIBODIES SYNAFFIX B.V. (NL) 2022-08-11 WO claimed
WO-2022058395-A1 ANTIBODY-EXATECAN CONJUGATES SYNAFFIX B.V. (NL) 2022-03-24 WO claimed
US-20260139067-A1 CDCP1 ANTIBODIES AND ANTIBODY DRUG CONJUGATES BETH ISRAEL DEACONESS MEDICAL CENTER (US) 2026-05-21 US disclosed
WO-2022049211-A1 METHODS FOR THE PREPARATION OF BIOCONJUGATES SYNAFFIX B.V. (NL) 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260139067-A1 CDCP1 ANTIBODIES AND ANTIBODY DRUG CONJUGATES DOCK2, CD2BP2, CDV3 SIRT6 4426/4885SIRT1 4743/4885FURIN 3771/4885
US-20250186606-A1 MODULAR LINKER COMPOUND FOR TARGET-BINDING DRUG CONJUGATES BCR, TBCD, TBC1D5 SIRT6 2231/4885SIRT1 3210/4885FURIN 1487/4885
US-20230357417-A1 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES SPECIFIC FOR CD123 AND USES THEREOF CD2, CD22, ENTPD3 SIRT6 2423/4885SIRT1 3666/4885FURIN 3828/4885
US-20250154270-A1 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES SPECIFIC FOR CD123 AND USES THEREOF CD2, CD22, ENTPD3 SIRT6 2423/4885SIRT1 3666/4885FURIN 3828/4885
US-11602525-B2 Antibody-drug conjugates with high drug loading GATD3, GLUL, SLC7A11 SIRT6 998/4885SIRT1 2337/4885FURIN 1601/4885
US-20230330245-A1 ANTIBODY-EXATECAN CONJUGATES ERBB3, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, IL23R SIRT6 2953/4885SIRT1 2419/4885FURIN 944/4885
US-11613581-B2 Antibodies and antibody-drug conjugates specific for CD123 and uses thereof CD2, CD22, ENTPD3 SIRT6 2423/4885SIRT1 3666/4885FURIN 3828/4885
US-20250262314-A1 MULTIFUNCTIONAL ANTIBODIES C1S, APOL1, BTN3A1 SIRT6 4675/4885SIRT1 4250/4885FURIN 1394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.