SCHEMBL29516648

SCHEMBL29516648

CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.78

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 8/20 0.78
▸ OPRM1 P35372 1/20 0.64
▸ OPRK1 P41145 1/20 0.64
▸ NMUR2 Q9GZQ4 2/20 0.62
▸ NMUR1 Q9HB89 2/20 0.62
▸ NTSR1 P30989 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29386868 0.94 OPRD1 (0.82) OPRD1OPRM1OPRK1NTSR1
SCHEMBL31197421 0.91 OPRD1 (0.77) OPRD1OPRM1OPRK1NMUR2NMUR1
SCHEMBL28101268 0.91 OPRD1 (0.66) OPRD1OPRM1OPRK1NMUR2NMUR1
SCHEMBL14889478 0.91 OPRD1 (0.66) OPRD1OPRM1OPRK1NMUR2NMUR1
SCHEMBL14889477 0.91 OPRD1 (0.66) OPRD1OPRM1OPRK1NMUR2NMUR1
SCHEMBL29648931 0.89 OPRD1 (0.90) OPRD1OPRM1OPRK1NTSR1
Dynorphin A (1-11) SCHEMBL30132402 0.89 OPRD1 (0.86) OPRD1OPRM1OPRK1NTSR1
Analog Of Dynorphin A SCHEMBL29389694 0.89 OPRD1 (0.86) OPRD1OPRM1OPRK1NTSR1
SCHEMBL31009049 0.89 OPRD1 (0.88) OPRD1OPRM1OPRK1NTSR1
SCHEMBL29878209 0.88 OPRD1 (0.85) OPRD1OPRM1OPRK1NTSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12590131-B2 Antimicrobial peptides with alpha-core helices LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER (US) 2026-03-31 — — US disclosed
US-20260049331-A1 Sense-and-Response of Proteins, Peptides, and Small Molecules Using Ligand-Induced Dimerization Activating RNA Editing (LIDAR) UNIV LELAND STANFORD JUNIOR (US) 2026-02-19 — — US disclosed
EP-3621632-B1 ANTIMICROBIAL PEPTIDES WITH ALPHA-CORE HELICES LOS ANGELES BIOMEDICAL RES INST HARBOR UCLA MEDICAL CT (US) 2025-08-13 — — EP disclosed
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME LONGEVITY BIOTECH, INC. 2024-11-14 — — US disclosed
US-20240279292-A1 ANTIMICROBIAL PEPTIDES WITH ALPHA-CORE HELICES LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER 2024-08-22 — — US disclosed
US-20240263161-A1 PEPTIDES WITH MUCIN-BINDING PROPERTIES UNIVERSITY OF COPENHAGEN (DK) 2024-08-08 — — US disclosed
US-11987607-B2 Antimicrobial peptides with alpha-core helices The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (US) 2024-05-21 — — US disclosed
EP-4347624-A1 PEPTIDES WITH MUCIN-BINDING PROPERTIES University of Copenhagen (DK) 2024-04-10 — — EP disclosed
CN-109312335-B Chimeric proteins and methods of modulating gene expression 斯坦福大学托管董事会 2023-10-24 — — CN disclosed
US-20230227516-A1 ANTIMICROBIAL PEPTIDES WITH ALPHA-CORE HELICES LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER 2023-07-20 — — US disclosed
EP-4168116-A1 TOPICAL FORMULATIONS OF (1S)-1-PHENYL-2-PYRIDIN-2-YLETHANAMINE Biohaven Therapeutics Ltd. (US) 2023-04-26 — — EP disclosed
CN-115836052-A Topical formulations of (1S) -1-phenyl-2-pyridin-2-ylethylamine 拜尔哈文制药股份有限公司 2023-03-21 — — CN disclosed
WO-2022253998-A1 PEPTIDES WITH MUCIN-BINDING PROPERTIES UNIVERSITY OF COPENHAGEN (DK) 2022-12-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590131-B2 Antimicrobial peptides with alpha-core helices VIP, HAMP, HM13 OPRD1 96/4885OPRM1 1215/4885OPRK1 703/4885
US-11987607-B2 Antimicrobial peptides with alpha-core helices VIP, NGLY1, SPPL2B OPRD1 1049/4885OPRM1 3306/4885OPRK1 3025/4885
US-20240279292-A1 ANTIMICROBIAL PEPTIDES WITH ALPHA-CORE HELICES VIP, NGLY1, SPPL2B OPRD1 1049/4885OPRM1 3306/4885OPRK1 3025/4885
US-20260049331-A1 Sense-and-Response of Proteins, Peptides, and Small Molecules Using Ligand-Induced Dimerization Activating RNA Editing (LIDAR) ADAR, ZFR, SLIRP OPRD1 2320/4885OPRM1 1894/4885OPRK1 2852/4885
US-20230227516-A1 ANTIMICROBIAL PEPTIDES WITH ALPHA-CORE HELICES VIP, NGLY1, SPPL2B OPRD1 1049/4885OPRM1 3306/4885OPRK1 3025/4885
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME SCTR, GIPR, APLNR OPRD1 501/4885OPRM1 674/4885OPRK1 364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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