Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11338454 | 0.98 | THRB (0.53) | THRBMAPTCTDSP1APOBEC3AAPOBEC3G | |
| Hydrochloric Acid SCHEMBL11554319 | 0.82 | CTDSP1 (0.49) | THRBMAPTCTDSP1APOBEC3AAPOBEC3G | |
| Hydrochloric Acid SCHEMBL3759338 | 0.80 | CTDSP1 (0.36) | THRBMAPTCTDSP1APOBEC3AAPOBEC3G | |
| Hydrochloric Acid SCHEMBL9635896 | 0.80 | CTDSP1 (0.51) | THRBMAPTCTDSP1APOBEC3AAPOBEC3G | |
| SCHEMBL11552985 | 0.79 | CTDSP1 (0.50) | THRBMAPTCTDSP1APOBEC3AAPOBEC3G | |
| SCHEMBL9118629 | 0.77 | CTDSP1 (0.37) | THRBMAPTCTDSP1APOBEC3AAPOBEC3G | |
| SCHEMBL19164699 | 0.77 | CTDSP1 (0.44) | THRBMAPTCTDSP1APOBEC3AAPOBEC3G | |
| Hydrochloric Acid SCHEMBL11552155 | 0.77 | CTDSP1 (0.35) | THRBMAPTCTDSP1APOBEC3AAPOBEC3G | |
| SCHEMBL9508592 | 0.71 | THRB (0.33) | THRB | |
| Hydrochloric Acid SCHEMBL11552150 | 0.71 | THRB (0.31) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4035145-A | FIXING AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-12 | — | — | US | claimed |
| EP-2616585-B1 | MODIFIED CELLULOSE FIBRES | SÖDRA SKOGSÄGARNA EKONOMISKA FÖRENING (SE) | 2014-07-23 | — | — | EP | disclosed |
| EP-2616585-A1 | MODIFIED CELLULOSE FIBRES | Södra Skogsägarna Ekonomiska Förening (SE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012034997-A1 | MODIFIED CELLULOSE FIBRES | SÖDRA SKOGSÄGARNA EKONOMISK FÖRENING (SE) | 2012-03-22 | — | — | WO | disclosed |
| EP-2428610-A1 | Modified cellulose fibres | Södra Skogsägarna ekonomisk förening (SE) | 2012-03-14 | — | — | EP | disclosed |
| CN-1786333-A | High-scratch-resistance high-wear-resistance metallized fabric and preparation method thereof | FUMAO INDUSTRY CO LTD (CN) | 2006-06-14 | — | — | CN | disclosed |
| EP-0574151-B1 | Process for improving the dyeability of fabrics and fibers | DOW CHEMICAL CO (US) | 1997-07-02 | — | — | EP | disclosed |
| US-5501711-A | OXIDATION, PADDING WITH CHITOSANS, STABILIZATION WITH A REDUCING AGENT | WATER & OIL TECHNOLOGIES, INC. (US) | 1996-03-26 | — | — | US | disclosed |
| US-5489313-A | INCREASING DYEABILITY OF TEXTILE FIBERS AND FABRICS BY PRETREATING WITH SODIUM HYDROXIDE AND AN EPOXY AMMONIUM SALT | AMERICAN EMULSIONS INC. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5330541-A | TREATING FIBERS OR FABRICS WITH DILUTE POTASSIUM HYDROXIDE, THEN WITH AN EPOXY AMMONIUM COMPOUND AND DYEING | AMERICAN EMULSIONS, CO. (US) | 1994-07-19 | — | — | US | disclosed |
| US-5320646-A | Process for improving the dyeability of fabrics and fibers | THE DOW CHEMICAL COMPANY (US) | 1994-06-14 | — | — | US | disclosed |
| EP-0574151-A1 | Process for improving the dyeability of fabrics and fibers | THE DOW CHEMICAL COMPANY (US) | 1993-12-15 | — | — | EP | disclosed |
| US-4366299-A | Copolymers containing fluorine and their use for the water-repellent and oil-repellent treatment of various substrates | P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1982-12-28 | — | — | US | disclosed |
| US-4246670-A | Process for improving the color yield and fastness properties of dyeings produced with anionic dyes on cellulose fibre material and cationic fibre-reactive compounds | CIBA-GEIGY CORPORATION (US) | 1981-01-27 | — | — | US | disclosed |
| US-4180664-A | Process for improving the color yield and fastness properties of dyeings produced with anionic dyes on cellulose fibre material and cationic fibre-reactive compounds | CIBA-GEIGY CORPORATION (US) | 1979-12-25 | — | — | US | disclosed |
| US-4171955-A | FIXING FIBER-REACTIVE DYES | CIBA-GEIGY CORPORATION (US) | 1979-10-23 | — | — | US | disclosed |
| US-4149849-A | FIXING ONTO CELLULOSE A HETEROCYCLIC QUATERNARY AMMONIUM EPOXIDE, ANIONIC DYE | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-17 | — | — | US | disclosed |
| US-4106903-A | IMPREGNATION WITH QUATERNARY AMMONIUM EPOXIDE FIXING AGENT AND WITH ADHESIVE, FIXING | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-15 | — | — | US | disclosed |
| US-4035145-A | FIXING AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-12 | — | — | US | disclosed |