Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3759338 | 0.78 | CTDSP1 (0.36) | CTDSP1APOBEC3AAPOBEC3GPOLBPABPC1 | |
| Hydrochloric Acid SCHEMBL9635896 | 0.78 | CTDSP1 (0.51) | CTDSP1APOBEC3AAPOBEC3GPOLBPABPC1 | |
| SCHEMBL11552985 | 0.78 | CTDSP1 (0.50) | CTDSP1APOBEC3AAPOBEC3GPOLBPABPC1 | |
| Hydrochloric Acid SCHEMBL295168 | 0.77 | THRB (0.51) | CTDSP1APOBEC3AAPOBEC3GPOLBPABPC1 | |
| SCHEMBL9118629 | 0.76 | CTDSP1 (0.37) | CTDSP1APOBEC3AAPOBEC3GPOLBPABPC1 | |
| SCHEMBL19164699 | 0.76 | CTDSP1 (0.44) | CTDSP1APOBEC3AAPOBEC3GPOLBPABPC1 | |
| SCHEMBL11338454 | 0.74 | THRB (0.53) | CTDSP1APOBEC3AAPOBEC3GPOLBPABPC1 | |
| SCHEMBL13770474 | 0.67 | ALDH1A1 (0.33) | CTDSP1APOBEC3AAPOBEC3GPOLBPABPC1 | |
| SCHEMBL19410338 | 0.65 | CTDSP1 (0.47) | CTDSP1APOBEC3AAPOBEC3GPOLBPABPC1 | |
| Hydrochloric Acid SCHEMBL10947882 | 0.64 | TP53 (0.31) | CTDSP1PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4149849-A | FIXING ONTO CELLULOSE A HETEROCYCLIC QUATERNARY AMMONIUM EPOXIDE, ANIONIC DYE | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-17 | — | — | US | disclosed |
| US-4035145-A | FIXING AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-12 | — | — | US | disclosed |