Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | ADH5 | P11766 | 1/20 | 0.42 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498590 | 1.00 | CDC25B (0.50) | CDC25BLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL3198016 | 0.86 | AR (0.43) | LMNAALDH1A1HSD17B10SRD5A2FFAR4 | |
| SCHEMBL30469486 | 0.86 | AR (0.43) | LMNAALDH1A1HSD17B10SRD5A2FFAR4 | |
| SCHEMBL6815102 | 0.85 | AR (0.42) | KDM4EALDH1A1HSD17B10FFAR4AR | |
| SCHEMBL403027 | 0.85 | CDC25B (0.46) | CDC25BLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL29835211 | 0.85 | CDC25B (0.46) | CDC25BLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL28503435 | 0.83 | DDR1 (0.43) | KDM4EALDH1A1HPGDHSD17B10FFAR4 | |
| SCHEMBL6315471 | 0.83 | KIF11 (0.50) | FFAR4ARDDR1SMN1; SMN2MAPT | |
| SCHEMBL7871444 | 0.82 | PBRM1 (0.51) | LMNAALDH1A1HPGDHSD17B10SRD5A2 | |
| SCHEMBL31319449 | 0.82 | RXRA (0.48) | KDM4ERXRARXRBRXRGSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568954-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE (CDK) 12 AND/OR CDK13 AND USES THEREOF | Insilico Medicine IP Limited (HK) | 2025-06-18 | — | — | EP | disclosed |
| CN-119677729-A | Cyclin Dependent Kinase (CDK) 12 and/or CDK13 inhibitors and uses thereof | 英矽智能科技知识产权有限公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-113164459-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-03 | — | — | CN | disclosed |
| WO-2024032561-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE (CDK) 12 AND/OR CDK13 AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-02-15 | — | — | WO | disclosed |
| CN-116457347-A | Compound containing condensed rings, application thereof and composition containing compound | 健艾仕生物医药有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-110177783-B | Hormone receptor modulators for the treatment of metabolic conditions and disorders | 阿德利克斯股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| WO-2022155357-A1 | POLY(IMIDE-OXADIAZOLE) MEMBRANES FOR GAS SEPARATION APPLICATIONS | SAUDI ARABIAN OIL COMPANY (SA) | 2022-07-21 | — | — | WO | disclosed |
| CN-114478482-A | Compound containing condensed ring, application thereof and composition containing compound | 健艾仕生物医药有限公司 | 2022-05-13 | — | — | CN | disclosed |