SCHEMBL29518554

SCHEMBL29518554

O=C(Nc1ccc(F)c(F)c1)c1nc2ccccc2[nH]1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.64
NPSR1 Q6W5P4 1/20 0.64
NPC1 O15118 5/20 0.54
RAB9A P51151 4/20 0.54
MAPT P10636 4/20 0.53
TP53 P04637 2/20 0.52
ROCK2 O75116 1/20 0.52
KDM4E B2RXH2 3/20 0.50
FAAH O00519 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
GAA P10253 1/20 0.49
PKM P14618 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
CHEK1 O14757 1/20 0.48
POLB P06746 1/20 0.48
THRB P10828 1/20 0.48
RECQL P46063 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28372909 1.00 LMNA (0.64) LMNANPSR1NPC1RAB9AMAPT
SCHEMBL29518293 0.85 FAAH (0.62) LMNANPC1RAB9AMAPTTP53
SCHEMBL28372959 0.85 FAAH (0.62) LMNANPC1RAB9AMAPTTP53
SCHEMBL28372986 0.82 RAB9A (0.71) LMNANPSR1NPC1RAB9AMAPT
SCHEMBL4437426 0.82 MMP2 (0.58) LMNANPC1RAB9AMAPTKDM4E
SCHEMBL28372308 0.82 NPC1 (0.54) LMNANPC1RAB9AMAPTROCK2
SCHEMBL29518652 0.82 NPC1 (0.54) LMNANPC1RAB9AMAPTROCK2
SCHEMBL9816236 0.81 FAAH (0.61) LMNANPC1RAB9AMAPTTP53
SCHEMBL28376649 0.80 RAB9A (0.65) LMNANPC1RAB9AMAPTTP53
SCHEMBL29086780 0.79 KMT2A (0.58) LMNANPC1RAB9AMAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110965064-B Application of alkylamide benzimidazole compound, organic weldable protective agent, preparation method, use method and application thereof 深圳市贝加电子材料有限公司 2022-04-29 CN disclosed