Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 3/20 | 0.56 |
| ▸ | NPY2R | P49146 | 3/20 | 0.56 |
| ▸ | NPY4R | P50391 | 3/20 | 0.56 |
| ▸ | MC4R | P32245 | 12/20 | 0.53 |
| ▸ | MC1R | Q01726 | 7/20 | 0.53 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.53 |
| ▸ | CCKBR | P32239 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31332219 | 0.87 | CCKBR (0.55) | KISS1RCCKBR | |
| SCHEMBL29559198 | 0.85 | NPY1R (0.65) | NPY1RNPY2RNPY4RMC4RMC1R | |
| SCHEMBL30366588 | 0.80 | KISS1R (0.60) | NPY1RNPY2RNPY4RMC4RKISS1R | |
| SCHEMBL29519296 | 0.80 | KISS1R (0.60) | NPY1RNPY2RNPY4RMC4RKISS1R | |
| SCHEMBL29373777 | 0.80 | NPY1R (0.74) | NPY1RNPY2RNPY4RMC4RMC1R | |
| SCHEMBL29526811 | 0.78 | ERAP2 (0.57) | — | |
| SCHEMBL31055392 | 0.76 | CCKBR (0.48) | NPY1RNPY2RNPY4RCCKBR | |
| SCHEMBL29805135 | 0.76 | NPY1R (0.79) | NPY1RNPY2RNPY4RMC4RMC1R | |
| SCHEMBL30797506 | 0.76 | NPY1R (0.79) | NPY1RNPY2RNPY4RMC4RMC1R | |
| SCHEMBL30169323 | 0.75 | OPRM1 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3973978-A1 | METHODS OF MODULATING CORTICOSTEROID RESPONSE | Mallinckrodt Ard IP Unlimited Company (IE) | 2022-03-30 | — | — | EP | disclosed |