SCHEMBL30366588

SCHEMBL30366588

CSCCC(N)C(=O)NC(CCC(=O)O)C(=O)NC(Cc1cnc[nH]1)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCN=C(N)N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCC(=O)O

nearest known ligand 0.65

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 2/20 0.60
▸ CCKBR P32239 3/20 0.58
▸ NPY1R P25929 3/20 0.56
▸ NPY2R P49146 3/20 0.56
▸ NPY4R P50391 3/20 0.56
▸ GHSR Q92847 5/20 0.55
▸ GRPR P30550 1/20 0.55
▸ CCKAR P32238 1/20 0.52
▸ MC4R P32245 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29519296 1.00 KISS1R (0.60) KISS1RCCKBRNPY1RNPY2RNPY4R
SCHEMBL30494060 0.97 KISS1R (0.60) KISS1RCCKBRNPY1RNPY2RNPY4R
SCHEMBL29849030 0.95 NPY1R (0.57) KISS1RCCKBRNPY1RNPY2RNPY4R
SCHEMBL30618455 0.95 NPY1R (0.57) KISS1RCCKBRNPY1RNPY2RNPY4R
SCHEMBL29519677 0.92 KISS1R (0.57) KISS1RCCKBRNPY1RNPY2RNPY4R
SCHEMBL29399016 0.85 GHSR (0.68) KISS1RNPY1RNPY2RNPY4RGHSR
SCHEMBL29402231 0.84 GHSR (0.69) KISS1RNPY1RNPY2RNPY4RGHSR
SCHEMBL29357687 0.84 KISS1R (0.62) KISS1RMC4R
SCHEMBL29559198 0.83 NPY1R (0.65) KISS1RCCKBRNPY1RNPY2RNPY4R
SCHEMBL31332219 0.80 CCKBR (0.55) KISS1RCCKBRCCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250127843-A1 ADRENOCORTICOTROPIC HORMONE PEPTIDE COMPOSITIONS AND METHODS OF USE FERRING B.V. (NL) 2025-04-24 — — US disclosed
EP-4404912-A1 ADRENOCORTICOTROPIC HORMONE PEPTIDE COMPOSITIONS AND METHODS OF USE Ferring B.V. (NL) 2024-07-31 — — EP disclosed
WO-2023046336-A1 ADRENOCORTICOTROPIC HORMONE PEPTIDE COMPOSITIONS AND METHODS OF USE FERRING B.V. (NL) 2023-03-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250127843-A1 ADRENOCORTICOTROPIC HORMONE PEPTIDE COMPOSITIONS AND METHODS OF USE MC2R, CRH, NR5A1 KISS1R 254/4885CCKBR 672/4885NPY1R 64/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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