SCHEMBL29519692

SCHEMBL29519692

NC(=O)[C@H](Cc1ccc2ccccc2c1)NCc1c[nH]c2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MC5R P33032 15/20 1.00
MC1R Q01726 6/20 1.00
MC3R P41968 10/20 0.60
MC4R P32245 5/20 0.60
MMP2 P08253 1/20 0.50
MMP7 P09237 1/20 0.50
MMP9 P14780 1/20 0.50
MMP8 P22894 1/20 0.50
MMP14 P50281 1/20 0.50
KCNT1 Q5JUK3 1/20 0.49
KDM4E B2RXH2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29367069 1.00 MC5R (1.00) MC5RMC1RMC3RMC4RMMP2
SCHEMBL29459408 0.91 MC5R (0.84) MC5RMC1RMC3RMC4RMMP2
SCHEMBL12464197 0.81 MC5R (0.68) MC5RMC1RMMP2MMP7MMP9
SCHEMBL12464359 0.81 MC5R (0.68) MC5RMC1RMMP2MMP7MMP9
SCHEMBL12464195 0.81 MC5R (0.68) MC5RMC1RMMP2MMP7MMP9
SCHEMBL27923213 0.79 KCNT1 (0.66) MC5RMC1RKCNT1KDM4E
SCHEMBL901464 0.79 KCNT1 (0.66) MC5RMC1RKCNT1KDM4E
SCHEMBL7932520 0.79 MC1R (0.64) MC5RMC1RMC3RMC4RMMP2
SCHEMBL24638062 0.77 MC5R (0.62) MC5RMC1RMC4RMMP2MMP7
SCHEMBL19199177 0.77 MC5R (0.62) MC5RMC1RMC4RMMP2MMP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12042523-B2 Compositions and methods for managing or improving bone disorders, joint disorders, cartilage disorders, or a combination thereof UNIGEN, INC. (US) 2024-07-23 US disclosed
US-20230201295-A1 Compositions and Methods for Managing or Improving Bone Disorders, Joint Disorders, Cartilage Disorders, or a Combination Thereof UNIGEN, INC. (US) 2023-06-29 US disclosed
US-20230190852-A1 COMPOSITIONS AND METHODS FOR JOINT HEALTH UNIGEN, INC. (US) 2023-06-22 US disclosed
CN-114854152-B Resin composition and product thereof 台光电子材料股份有限公司 2023-05-23 CN disclosed
US-11554153-B2 Compositions and methods for managing or improving bone disorders, joint disorders, cartilage disorders, or a combination thereof UNIGEN, INC. (US) 2023-01-17 US disclosed
US-11453771-B2 Resin composition and article made therefrom Elite Material Co., Ltd. (TW) 2022-09-27 US disclosed
CN-114854152-A Resin composition and product thereof 台光电子材料股份有限公司 2022-08-05 CN disclosed
US-20220243046-A1 RESIN COMPOSITION AND ARTICLE MADE THEREFROM Elite Material Co., Ltd. (TW) 2022-08-04 US disclosed
CN-112800518-B Stratum surface model correction method utilizing adjacent stratum cross-correlation constraint 中国地质大学(武汉) 2022-04-12 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12042523-B2 Compositions and methods for managing or improving bone disorders, joint disorders, cartilage disorders, or a combination thereof MATR3, ACACA, COL2A1 MC5R 2879/4885MC1R 4062/4885MC3R 1499/4885
US-11554153-B2 Compositions and methods for managing or improving bone disorders, joint disorders, cartilage disorders, or a combination thereof MATR3, ACACA, COL2A1 MC5R 2879/4885MC1R 4062/4885MC3R 1499/4885
US-20230201295-A1 Compositions and Methods for Managing or Improving Bone Disorders, Joint Disorders, Cartilage Disorders, or a Combination Thereof MATR3, ACACA, COL2A1 MC5R 2879/4885MC1R 4062/4885MC3R 1499/4885
US-20230190852-A1 COMPOSITIONS AND METHODS FOR JOINT HEALTH PTGES, PTGES3, PTGES2 MC5R 3686/4885MC1R 4415/4885MC3R 2617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.