Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 5/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23638475 | 1.00 | MTNR1A (0.39) | MTNR1AMTNR1BIRAK4TDP1LPL | |
| SCHEMBL29520169 | 0.90 | MAPT (0.40) | IRAK4TDP1LPLLIPGF11 | |
| SCHEMBL15288424 | 0.85 | LPL (0.41) | IRAK4LPLLIPGEGFRIDO1 | |
| SCHEMBL17678218 | 0.85 | MEN1 (0.51) | MTNR1AMTNR1BIRAK4TDP1LPL | |
| SCHEMBL17678298 | 0.85 | HTR6 (0.39) | MTNR1AMTNR1BIRAK4TDP1LPL | |
| SCHEMBL2144110 | 0.83 | MTNR1A (0.49) | MTNR1AMTNR1BIRAK4LIPGIDO1 | |
| SCHEMBL18731879 | 0.83 | TGFBR1 (0.40) | MTNR1AMTNR1BIRAK4LPLLIPG | |
| SCHEMBL18731880 | 0.83 | HDAC1 (0.39) | MTNR1AMTNR1BIRAK4TDP1 | |
| SCHEMBL29463875 | 0.82 | FFAR1 (0.48) | MTNR1AMTNR1BIRAK4LPLLIPG | |
| SCHEMBL18638308 | 0.82 | FFAR1 (0.48) | MTNR1AMTNR1BIRAK4LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| CN-114901664-A | Pyridone compound and application thereof | 江苏先声药业有限公司 | 2022-08-12 | — | — | CN | disclosed |
| WO-2022063140-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AS HPK1 MODULATOR AND METHODS USING SAME | SHENZHEN IONOVA LIFE SCIENCE CO., LTD. (CN) | 2022-03-31 | — | — | WO | disclosed |