Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2957074 | 0.83 | DRD3 (0.49) | ALDH1A1DRD3ADRA2CADRA1B | |
| SCHEMBL2952098 | 0.75 | LMNA (0.50) | MEN1KMT2ALMNAALDH1A1SIRT6 | |
| SCHEMBL20567915 | 0.74 | MAPT (0.48) | LMNAALDH1A1SIRT6MAPTADRA2A | |
| SCHEMBL2077591 | 0.70 | DRD3 (0.67) | DRD3 | |
| SCHEMBL2773139 | 0.69 | SIRT6 (0.55) | MEN1KMT2AALDH1A1DRD3SIRT6 | |
| SCHEMBL520652 | 0.69 | KMT2A (0.50) | MEN1KMT2APKMLMNAALDH1A1 | |
| SCHEMBL27873292 | 0.69 | CNR2 (0.48) | MEN1KMT2AALDH1A1DRD3DRD4 | |
| SCHEMBL20490713 | 0.68 | QDPR (0.60) | LMNAALDH1A1SIRT6MAPTHTT | |
| SCHEMBL20490700 | 0.68 | CCR5 (0.45) | MEN1KMT2ALMNAALDH1A1SIRT6 | |
| SCHEMBL2299650 | 0.68 | KCNJ1 (0.47) | MEN1KMT2AALDH1A1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | disclosed |