SCHEMBL2952158

SCHEMBL2952158

CCCCC(CC)(CO)COP(O)Oc1c(C(C)(C)C)cc(C)cc1C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2951546 0.91 NR5A2 (0.32)
SCHEMBL3995929 0.86 SMN1; SMN2 (0.37) CYP3A4CYP2D6
SCHEMBL2952154 0.85 CYP3A4 (0.34) CYP3A4CYP2D6
Butylated Hydroxytoluene SCHEMBL2952153 0.82 CA2 (0.43) CYP3A4CYP2D6
SCHEMBL3671836 0.78 SMN1; SMN2 (0.41) CYP3A4CYP2D6
SCHEMBL16689991 0.78 RXRA (0.34)
SCHEMBL28319554 0.77 S1PR1 (0.32)
Butylated Hydroxytoluene SCHEMBL2952160 0.76 ALDH1A1 (0.50) CYP3A4CYP2D6
SCHEMBL2951542 0.76 NR5A2 (0.36)
SCHEMBL2748349 0.76 NR5A2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2864310-B1 STABILIZER COMPOSITIONS CONTAINING SUBSTITUTED CHROMAN COMPOUNDS AND METHODS OF USE CYTEC TECH CORP (US) 2022-10-26 EP claimed
US-20220212375-A1 POLYMERIC HOLLOW ARTICLES CONTAINING CHROMAN-BASED COMPOUNDS AND MADE BY ROTATIONAL MOLDING CYTEC TECHNOLOGY CORP. 2022-07-07 US claimed
US-20220153959-A1 POLYOLEFIN COMPOSITIONS CONTAINING SUBSTITUTED CHROMAN COMPOUNDS AND MOLDED ARTICLES PRODUCED THEREFROM CYTEC TECHNOLOGY CORP. 2022-05-19 US claimed
US-10975278-B2 Granular stabilizer compositions for use in polymer resins and methods of making same CYTEC INDUSTRIES INC. (US) 2021-04-13 US claimed
EP-2652014-B1 PROCESSING ADDITIVES AND USES OF SAME IN ROTATIONAL MOLDING CYTEC TECH CORP (US) 2020-07-01 EP claimed
US-20190264084-A1 GRANULAR STABILIZER COMPOSITIONS FOR USE IN POLYMER RESINS AND METHODS OF MAKING SAME CYTEC INDUSTRIES INC. (US) 2019-08-29 US claimed
US-20130145962-A1 Stabilizer Compositions Containing Substituted Chroman Compounds and Methods of Use CYTEC TECHNOLOGY CORP. (US) 2013-06-13 US claimed
US-20120146257-A1 PROCESSING ADDITIVES AND USES OF SAME IN ROTATIONAL MOLDING CYTEC TECHNOLOGY CORP. (US) 2012-06-14 US claimed
US-20100256266-A1 STABILIZER COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 2010-10-07 US claimed
US-7759417-B2 Stabilizer compositions CYTEC TECHNOLOGY CORP. (US) 2010-07-20 US claimed
US-20090149581-A1 STABILIZER COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 2009-06-11 US claimed
WO-2007136565-A1 STABILIZER COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 2007-11-29 WO claimed
EP-2864310-B1 STABILIZER COMPOSITIONS CONTAINING SUBSTITUTED CHROMAN COMPOUNDS AND METHODS OF USE CYTEC TECH CORP (US) 2022-10-26 EP disclosed
US-20220212375-A1 POLYMERIC HOLLOW ARTICLES CONTAINING CHROMAN-BASED COMPOUNDS AND MADE BY ROTATIONAL MOLDING CYTEC TECHNOLOGY CORP. 2022-07-07 US disclosed
US-20220153959-A1 POLYOLEFIN COMPOSITIONS CONTAINING SUBSTITUTED CHROMAN COMPOUNDS AND MOLDED ARTICLES PRODUCED THEREFROM CYTEC TECHNOLOGY CORP. 2022-05-19 US disclosed
US-11312043-B2 Processing additives and uses of same in rotational molding CYTEC TECHNOLOGY CORP. (US) 2022-04-26 US disclosed
US-20120146257-A1 PROCESSING ADDITIVES AND USES OF SAME IN ROTATIONAL MOLDING CYTEC TECHNOLOGY CORP. (US) 2012-06-14 US disclosed
US-20100256266-A1 STABILIZER COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 2010-10-07 US disclosed
US-7759417-B2 Stabilizer compositions CYTEC TECHNOLOGY CORP. (US) 2010-07-20 US disclosed
US-20090149581-A1 STABILIZER COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 2009-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220212375-A1 POLYMERIC HOLLOW ARTICLES CONTAINING CHROMAN-BASED COMPOUNDS AND MADE BY ROTATIONAL MOLDING RPS7, MRPS27, F7 CYP3A4 2620/4885CYP2D6 4217/4885
US-20220153959-A1 POLYOLEFIN COMPOSITIONS CONTAINING SUBSTITUTED CHROMAN COMPOUNDS AND MOLDED ARTICLES PRODUCED THEREFROM NOTUM, PMM2, WASF2 CYP3A4 1882/4885CYP2D6 2998/4885
US-11312043-B2 Processing additives and uses of same in rotational molding MCM4, MCM5, GRN CYP3A4 1268/4885CYP2D6 3795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.