SCHEMBL2952167

SCHEMBL2952167

CO[Si](Cc1ccc(CCBr)cc1)(OC)OC

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.43
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TAAR1 Q96RJ0 2/20 0.32
TSHR P16473 1/20 0.31
ESR1 P03372 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2953179 0.88 CALM1 (0.35) TDP1MEN1KMT2ATAAR1
SCHEMBL415828 0.84 ESR1 (0.39) TAAR1TSHRESR1SMN1; SMN2
SCHEMBL2955540 0.83 TRPA1 (0.39) TSHRESR1
SCHEMBL2945709 0.80 TDP1 (0.40) TDP1MEN1KMT2ATAAR1
SCHEMBL2955545 0.79 TAAR1 (0.32) TAAR1TSHRESR1SMN1; SMN2
SCHEMBL3361270 0.78 ESR1 (0.32) ESR1
SCHEMBL17529742 0.78 TAAR1 (0.43) MEN1KMT2ATAAR1
SCHEMBL2944384 0.78 TRPA1 (0.34) TSHR
SCHEMBL2954750 0.76 CALM1 (0.35) TAAR1
SCHEMBL988626 0.76 AGXT (0.43) TDP1TAAR1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7759406-B2 Process for producing polysilsesquioxane graft polymer, pressure-sensitive adhesive, and pressure-sensitive adhesive sheet LINTEC CORPORATION (JP) 2010-07-20 US disclosed
US-20080051487-A1 Process for Producing Polysilsesquioxane Graft Polymer, Pressure-Sensitive Adhesive, and Pressure-Sensitive Adhesive Sheet LINTEC CORPORATION (JP) 2008-02-28 US disclosed