Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10386779 | 0.79 | MITF (0.39) | POLBHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL295286 | 0.75 | KMT2A (0.44) | POLBHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL294590 | 0.71 | CYP3A4 (0.44) | POLBHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL9863399 | 0.69 | ALDH1A1 (0.59) | POLBHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL7551286 | 0.67 | MITF (0.36) | ALDH1A1L3MBTL1HTT | |
| SCHEMBL3181495 | 0.67 | ALDH1A1 (0.61) | POLBHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL29964300 | 0.67 | ALDH1A1 (0.61) | POLBHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL12190885 | 0.67 | CYP3A4 (0.47) | POLBHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL21869784 | 0.66 | ALDH1A1 (0.55) | POLBHSD17B10ALDH1A1KMT2AMEN1 | |
| Ethylene SCHEMBL19616645 | 0.65 | ALDH1A1 (0.57) | POLBHSD17B10ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2128140-B1 | METHOD FOR PRODUCING 2-NITROIMIDAZOLE DERIVATIVE | POLA PHARMA INC (JP) | 2012-03-14 | — | — | EP | claimed |