SCHEMBL29523656

SCHEMBL29523656

O=c1ccn([C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]3O[C@@H](n4ccc(=O)[nH]c4=O)[C@H](O)[C@@H]3O)C3OC(Cc4ccccc4)OC32)c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 15/20 1.00
P2RY12 Q9H244 8/20 1.00
P2RY6 Q15077 8/20 1.00
P2RY4 P51582 3/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2609286 1.00 P2RY2 (1.00) P2RY2P2RY12P2RY6P2RY4
SCHEMBL14017335 0.92 P2RY12 (0.93) P2RY2P2RY12P2RY6P2RY4
SCHEMBL13614504 0.92 P2RY12 (0.93) P2RY2P2RY12P2RY6P2RY4
SCHEMBL14017138 0.91 P2RY12 (0.92) P2RY2P2RY12P2RY6
SCHEMBL13614414 0.91 P2RY12 (0.92) P2RY2P2RY12P2RY6
SCHEMBL16325914 0.89 P2RY12 (0.89) P2RY2P2RY12P2RY6
SCHEMBL13614505 0.89 P2RY12 (0.89) P2RY2P2RY12P2RY6
SCHEMBL14017142 0.89 P2RY12 (0.87) P2RY2P2RY12P2RY6
SCHEMBL13614410 0.89 P2RY12 (0.87) P2RY2P2RY12P2RY6
SCHEMBL14017330 0.88 P2RY12 (0.86) P2RY2P2RY12P2RY6P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250345353-A1 COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS ASTROCYTE PHARMACEUTICALS INC (US) 2025-11-13 US disclosed
US-12390483-B2 Compounds and methods for treating neurological and cardiovascular conditions ASTROCYTE PHARMACEUTICALS, INC. (US) 2025-08-19 US disclosed
US-20250177405-A1 METHODS OF TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS ASTROCYTE PHARMACEUTICALS, INC. 2025-06-05 US disclosed
US-12239654-B2 Compounds and methods for treating neurological and cardiovascular conditions ASTROCYTE PHARMACEUTICALS, INC. (US) 2025-03-04 US disclosed
EP-4436567-A1 METHODS OF TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS Astrocyte Pharmaceuticals, Inc. (US) 2024-10-02 EP disclosed
EP-4414027-A2 COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS Astrocyte Pharmaceuticals, Inc. (US) 2024-08-14 EP disclosed
EP-3445368-B1 COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS ASTROCYTE PHARMACEUTICALS INC (US) 2024-07-17 EP disclosed
US-11839615-B2 Compounds and methods for treating addiction and related disorders ASTROCYTE PHARMACEUTICALS, INC. (US) 2023-12-12 US disclosed
EP-4240339-A1 COMPOSITIONS AND METHODS TO PROMOTE THYMIC FUNCTION Fred Hutchinson Cancer Center (US) 2023-09-13 EP disclosed
US-20230263800-A1 COMPOSITIONS AND METHODS TO PROMOTE THYMIC FUNCTION FRED HUTCHINSON CANCER CENTER (US) 2023-08-24 US disclosed
US-20230165887-A1 COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2023-06-01 US disclosed
WO-2023091791-A1 METHODS OF TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS ASTROCYTE PHARMACEUTICALS, INC. (US) 2023-05-25 WO disclosed
US-11484545-B2 Compounds and methods for treating neurological and cardiovascular conditions ASTROCYTE PHARMACEUTICALS, INC. (US) 2022-11-01 US disclosed
US-20220305044-A1 COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2022-09-29 US disclosed
CN-114903903-A Compounds and methods for treating neurological and cardiovascular conditions 阿斯特罗赛特制药公司 2022-08-16 CN disclosed
WO-2022098776-A1 COMPOSITIONS AND METHODS TO PROMOTE THYMIC FUNCTION FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2022-05-12 WO disclosed
CN-109310695-B Compounds and methods for treating neurological and cardiovascular conditions 阿斯特罗赛特制药公司 2022-04-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12390483-B2 Compounds and methods for treating neurological and cardiovascular conditions TNNI3, CPT1B, TNNT2 P2RY2 1796/4885P2RY12 2119/4885P2RY6 1659/4885
US-11839615-B2 Compounds and methods for treating addiction and related disorders ADORA2A, TAAR5, ADORA3 P2RY2 119/4885P2RY12 300/4885P2RY6 151/4885
US-20250345353-A1 COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS TNNI3, CPT1B, TNNT2 P2RY2 1796/4885P2RY12 2119/4885P2RY6 1659/4885
US-20230263800-A1 COMPOSITIONS AND METHODS TO PROMOTE THYMIC FUNCTION BMP4, P2RY2, GPR39 P2RY2 2/4885P2RY12 7/4885P2RY6 21/4885
US-11484545-B2 Compounds and methods for treating neurological and cardiovascular conditions TNNI3, CPT1B, TNNT2 P2RY2 1796/4885P2RY12 2119/4885P2RY6 1659/4885
US-20220305044-A1 COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS TNNI3, CPT1B, TNNT2 P2RY2 1796/4885P2RY12 2119/4885P2RY6 1659/4885
US-20250177405-A1 METHODS OF TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS ADORA2A, ADORA3, ADORA1 P2RY2 9/4885P2RY12 20/4885P2RY6 24/4885
US-12239654-B2 Compounds and methods for treating neurological and cardiovascular conditions TNNI3, CPT1B, TNNT2 P2RY2 1796/4885P2RY12 2119/4885P2RY6 1659/4885
US-20230165887-A1 COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS TNNI3, CPT1B, TNNT2 P2RY2 1796/4885P2RY12 2119/4885P2RY6 1659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.