SCHEMBL2952473

SCHEMBL2952473

CCO[Si](Cc1ccc(CCCCl)cc1)(OCC)OCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33
MAPT P10636 2/20 0.32
RAB9A P51151 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ALDH1A1 P00352 3/20 0.32
HSD17B10 Q99714 3/20 0.32
ESR1 P03372 2/20 0.32
ADRA2A P08913 2/20 0.32
ADORA3 P0DMS8 2/20 0.32
TACR2 P21452 2/20 0.32
SLC6A2 P23975 2/20 0.32
SLC6A4 P31645 2/20 0.32
SLC6A3 Q01959 2/20 0.32
KDM4E B2RXH2 2/20 0.32
LMNA P02545 1/20 0.32
SHBG P04278 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
HSPD1 P10809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2951509 0.89 AKT1 (0.32)
SCHEMBL16062870 0.82 ESR1 (0.36) ESR1
SCHEMBL2951768 0.82 THRA (0.34) THRATHRBALDH1A1HSD17B10ESR1
SCHEMBL2954750 0.81 CALM1 (0.35) THRATHRBCALM1HRH3
SCHEMBL2956037 0.81 CA1 (0.32) ESR1CA1CA2
SCHEMBL2947258 0.79 THRA (0.33) THRATHRBMAPTRAB9AL3MBTL1
SCHEMBL28045043 0.78 LMNA (0.33) MAPTRAB9AL3MBTL1ALDH1A1HSD17B10
SCHEMBL2945709 0.78 TDP1 (0.40) MEN1KMT2A
SCHEMBL320387 0.77 TAAR1 (0.41) THRBRAB9AALDH1A1SLC6A2SLC6A4
SCHEMBL27094922 0.77 HRH3 (0.37) MAPTRAB9AL3MBTL1HSD17B10ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7759406-B2 Process for producing polysilsesquioxane graft polymer, pressure-sensitive adhesive, and pressure-sensitive adhesive sheet LINTEC CORPORATION (JP) 2010-07-20 US disclosed
US-20080051487-A1 Process for Producing Polysilsesquioxane Graft Polymer, Pressure-Sensitive Adhesive, and Pressure-Sensitive Adhesive Sheet LINTEC CORPORATION (JP) 2008-02-28 US disclosed