Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.36 |
| ▸ | ATF4 | P18848 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29525831 | 0.85 | RXFP1 (0.45) | RORCLMNARXFP1 | |
| SCHEMBL29525089 | 0.83 | DRD2 (0.47) | MAPTPPARGPPARADPP8DPP9 | |
| SCHEMBL31560408 | 0.83 | CYP17A1 (0.41) | DPP8DPP9 | |
| SCHEMBL21238259 | 0.83 | DPP8 (0.43) | HTTDPP8DPP9 | |
| SCHEMBL28392276 | 0.82 | LMNA (0.43) | MAPTPPARGPPARALMNADPP8 | |
| SCHEMBL31736668 | 0.81 | CA1 (0.39) | MAPTDPP8DPP9 | |
| SCHEMBL31736645 | 0.81 | MIF (0.38) | RORCMAPTDPP8DPP9 | |
| SCHEMBL31737017 | 0.81 | DPP8 (0.38) | PPARGPPARADPP8DPP9 | |
| SCHEMBL19282962 | 0.77 | PDE2A (0.46) | RORCMAPTPPARGPPARAPDE2A | |
| SCHEMBL19953326 | 0.77 | RORC (0.41) | RORCMAPTPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11242327-B2 | Analgesic compounds | RECURIUM IP HOLDINGS, LLC (US) | 2022-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11242327-B2 | Analgesic compounds | INA, IK, ACHE | RORC 1039/4885MAPT 2670/4885PPARG 904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.