SCHEMBL29526053

SCHEMBL29526053

CC(C)C1=C(O)C2=C(C[C@]34CCC[C@](C)(C(=O)O3)[C@H]4C=C2)C(=O)C1=O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ EP300 Q09472 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31150123 1.00 EP300 (0.31) EP300
SCHEMBL22861893 0.68 EP300 (0.41) EP300
SCHEMBL29784877 0.57 CACNA1G (0.45) EP300
SCHEMBL33720869 0.56 EP300 (0.38) EP300
Royleanone SCHEMBL16006778 0.55 CYP3A4 (0.44) EP300
Royleanone SCHEMBL21291506 0.55 CYP3A4 (0.44) EP300
SCHEMBL22861899 0.55 EP300 (0.42) EP300
SCHEMBL22861898 0.55 EP300 (0.42) EP300
SCHEMBL31237632 0.55 EP300 (0.39) EP300
SCHEMBL22861880 0.55 EP300 (0.64) EP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022142160-A1 APPLICATION OF ICETEXANE-TYPE ABIETANE DITERPENE IN PREPARATION OF DRUG FOR TREATING COLORECTAL CANCER 中南大学 2022-07-07 — — WO claimed
WO-2022142159-A1 PREPARATION METHOD FOR ICETEXANE TYPE ABIETANE DITERPENE 中南大学 2022-07-07 — — WO claimed
CN-112618530-B Application of Icetexane type abietane diterpene in preparation of colorectal cancer treatment drug 中南大学 2022-04-01 — — CN claimed
CN-112707795-B Preparation method of Icetexane type abietane diterpene 中南大学 2022-04-01 — — CN claimed
US-20250387311-A1 SCLAREOL OR SCLAREOLIDE FOR IMPROVING SCALP CONDITIONS AND HAIR GROWTH ISP INVESTMENTS LLC (US) 2025-12-25 — — US disclosed
US-20250263377-A1 METHODS AND COMPOSITIONS FOR TERPENOID TRICYCLOALKANE SYNTHESIS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2025-08-21 — — US disclosed
US-20250177347-A1 SCLAREOL OR SCLAREOLIDE FOR USE IN THE TREATMENT OF INFLAMMATORY SKIN CONDITIONS ISP INVESTMENTS LLC (US) 2025-06-05 — — US disclosed
US-12312314-B2 Methods and compositions for terpenoid tricycloalkane synthesis UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2025-05-27 — — US disclosed
US-20250154106-A1 ABIETANES AND METHODS OF MAKING AND USING THE SAME NATIONAL INSTITUTES OF HEALTH 2025-05-15 — — US disclosed
CN-119604482-A Taxin analogues and methods of use thereof 曜煜生物医药集团有限公司 2025-03-11 — — CN disclosed
US-12221419-B2 Abietanes and methods of making and using the same FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2025-02-11 — — US disclosed
EP-4499055-A2 ABIETANES AND METHODS OF MAKING AND USING THE SAME The Florida State University Research Foundation, Incorporated (US) 2025-02-05 — — EP disclosed
WO-2022142159-A1 PREPARATION METHOD FOR ICETEXANE TYPE ABIETANE DITERPENE 中南大学 2022-07-07 — — WO disclosed
WO-2022142159-A1 PREPARATION METHOD FOR ICETEXANE TYPE ABIETANE DITERPENE 中南大学 2022-07-07 — — WO disclosed
CN-112618530-B Application of Icetexane type abietane diterpene in preparation of colorectal cancer treatment drug 中南大学 2022-04-01 — — CN disclosed
CN-112618530-B Application of Icetexane type abietane diterpene in preparation of colorectal cancer treatment drug 中南大学 2022-04-01 — — CN disclosed
CN-112618530-B Application of Icetexane type abietane diterpene in preparation of colorectal cancer treatment drug 中南大学 2022-04-01 — — CN disclosed
CN-112707795-B Preparation method of Icetexane type abietane diterpene 中南大学 2022-04-01 — — CN disclosed
CN-112707795-B Preparation method of Icetexane type abietane diterpene 中南大学 2022-04-01 — — CN disclosed
CN-112707795-B Preparation method of Icetexane type abietane diterpene 中南大学 2022-04-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263377-A1 METHODS AND COMPOSITIONS FOR TERPENOID TRICYCLOALKANE SYNTHESIS LSS, GGPS1, DHPS EP300 3928/4885
US-20250387311-A1 SCLAREOL OR SCLAREOLIDE FOR IMPROVING SCALP CONDITIONS AND HAIR GROWTH CUTA, SUCLG1, NACA EP300 1301/4885
US-20250154106-A1 ABIETANES AND METHODS OF MAKING AND USING THE SAME SYMPK, TXK, HYPK EP300 3262/4885
US-12312314-B2 Methods and compositions for terpenoid tricycloalkane synthesis LSS, GGPS1, DHPS EP300 3928/4885
US-12221419-B2 Abietanes and methods of making and using the same SYMPK, TXK, HYPK EP300 3262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback