Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953991 | 0.91 | RXFP1 (0.43) | MEN1KMT2ANPC1GAARAB9A | |
| SCHEMBL12116536 | 0.91 | RXFP1 (0.43) | MEN1KMT2ANPC1GAARAB9A | |
| SCHEMBL4689617 | 0.84 | AAK1 (0.44) | MEN1KMT2ANPC1GAARAB9A | |
| SCHEMBL29662262 | 0.82 | IDO1 (0.54) | MEN1KMT2ANPC1GAARAB9A | |
| SCHEMBL19002107 | 0.82 | MEN1 (0.43) | MEN1KMT2ANPC1GAARAB9A | |
| SCHEMBL367901 | 0.82 | IDO1 (0.54) | MEN1KMT2ANPC1GAARAB9A | |
| SCHEMBL1008543 | 0.81 | LMNA (0.47) | MEN1KMT2ANPC1GAARAB9A | |
| SCHEMBL29525132 | 0.81 | LMNA (0.47) | MEN1KMT2ANPC1GAARAB9A | |
| SCHEMBL593832 | 0.81 | MEN1 (0.44) | MEN1KMT2ANPC1GAARAB9A | |
| SCHEMBL12596121 | 0.81 | RXFP1 (0.43) | MEN1KMT2ANPC1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070274922-A1 | Water Soluble Boronic Acid Fluorescent Reporter Compounds and Methods of Use Thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-11-29 | — | — | US | claimed |
| WO-2005024416-A1 | WATER SOLUBLE BORONIC ACID FLUORESCENT REPORTER COMPOUNDS AND METHODS OF USE THEREOF | WANG BINGHE (US) | 2005-03-17 | — | — | WO | claimed |
| US-7767817-B2 | Water soluble boronic acid fluorescent reporter compounds and methods of use thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-08-03 | — | — | US | disclosed |
| US-7714127-B2 | Process for making heteroaryl amine intermediate compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2010-05-11 | — | — | US | disclosed |
| US-7714127-B2 | Process for making heteroaryl amine intermediate compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2010-05-11 | — | — | US | disclosed |
| EP-1409460-B1 | NOVEL SYNTHESIS OF HETEROARYLAMINE INTERMEDIATE COMPOUNDS | BOEHRINGER INGELHEIM PHARMA (US) | 2010-03-24 | — | — | EP | disclosed |
| US-20070274922-A1 | Water Soluble Boronic Acid Fluorescent Reporter Compounds and Methods of Use Thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-11-29 | — | — | US | disclosed |
| US-20070105857-A1 | Process for Making Heteroaryl Amine Intermediate Compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. | 2007-05-10 | — | — | US | disclosed |
| US-20070105857-A1 | Process for Making Heteroaryl Amine Intermediate Compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. | 2007-05-10 | — | — | US | disclosed |
| WO-2007044490-A2 | PROCESS FOR MAKING HETEROARYL AMINE INTERMEDIATE COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-04-19 | — | — | WO | disclosed |
| US-7022883-B2 | Preparation of aryl intermediates | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-04-04 | — | — | US | disclosed |
| EP-1565477-A1 | PREPARATION OF ARYL INTERMEDIATE COMPOUNDS USING TRIALKYLMAGNESATE REAGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2005-08-24 | — | — | EP | disclosed |
| WO-2005024416-A1 | WATER SOLUBLE BORONIC ACID FLUORESCENT REPORTER COMPOUNDS AND METHODS OF USE THEREOF | WANG BINGHE (US) | 2005-03-17 | — | — | WO | disclosed |
| US-6825184-B2 | FOR USE AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2004-11-30 | — | — | US | disclosed |
| WO-2004048389-A1 | PREPARATION OF ARYL INTERMEDIATES COMPOUNDS USING TRIALKYLMAGNESATE REAGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2004-06-10 | — | — | WO | disclosed |
| US-20040106807-A1 | Preparation of aryl intermediates | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2004-06-03 | — | — | US | disclosed |
| US-20030162968-A1 | 1,4-Disubstituted benzo-fused urea compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106807-A1 | Preparation of aryl intermediates | CYP1A1, CYP1B1, UGT1A1 | MEN1 2450/4885KMT2A 1821/4885NPC1 677/4885 |
| US-20030162968-A1 | 1,4-Disubstituted benzo-fused urea compounds | NFKBIA, MPO, RELA | MEN1 3850/4885KMT2A 3421/4885NPC1 1708/4885 |
| US-20070274922-A1 | Water Soluble Boronic Acid Fluorescent Reporter Compounds and Methods of Use Thereof | GUSB, BLVRB, BCL6 | MEN1 1304/4885KMT2A 3814/4885NPC1 166/4885 |
| US-20070105857-A1 | Process for Making Heteroaryl Amine Intermediate Compounds | MAOB, MAOA, CYP1B1 | MEN1 138/4885KMT2A 1632/4885NPC1 372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.