Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.58 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.54 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.54 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | CTSC | P53634 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29590137 | 1.00 | MMP2 (0.58) | MMP2ERAP2LNPEPPSMB1PSMB8 | |
| SCHEMBL30434967 | 0.93 | MMP2 (0.51) | MMP2ERAP2LNPEPPSMB1PSMB8 | |
| SCHEMBL7872647 | 0.91 | OPRD1 (0.56) | MMP2OPRK1 | |
| SCHEMBL7872640 | 0.91 | OPRD1 (0.56) | MMP2OPRK1 | |
| SCHEMBL31253360 | 0.91 | LNPEP (0.56) | MMP2ERAP2LNPEPOPRK1 | |
| SCHEMBL29424183 | 0.91 | MMP2 (0.61) | MMP2ERAP2LNPEPOPRK1 | |
| SCHEMBL30478748 | 0.89 | MMP2 (0.55) | MMP2OPRK1 | |
| SCHEMBL13167829 | 0.88 | MMP2 (0.53) | MMP2ERAP2LNPEPPSMB1PSMB8 | |
| SCHEMBL29403606 | 0.86 | SLC15A1 (0.54) | OPRK1CTSC | |
| SCHEMBL29630365 | 0.86 | ERAP2 (0.62) | MMP2ERAP2LNPEPOPRK1CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230393140-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2023-12-07 | — | — | US | disclosed |
| EP-4229211-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI International (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022082006-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2022-04-21 | — | — | WO | disclosed |