SCHEMBL29535027

SCHEMBL29535027

C[C@H](NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CPB2 Q96IY4 15/20 0.46
▸ DPP7 Q9UHL4 1/20 0.45
▸ MEN1 O00255 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ GHSR Q92847 1/20 0.42
▸ FOLH1 Q04609 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29802044 0.98 CPB2 (0.47) CPB2DPP7MEN1KMT2AGHSR
SCHEMBL29801990 0.97 CPB2 (0.46) CPB2DPP7MEN1KMT2AGHSR
SCHEMBL31688033 0.97 CPB2 (0.47) CPB2DPP7MEN1KMT2AGHSR
SCHEMBL29802039 0.92 GHSR (0.43) CPB2DPP7MEN1KMT2AGHSR
SCHEMBL29802071 0.92 GHSR (0.43) CPB2DPP7MEN1KMT2AGHSR
SCHEMBL29368001 0.91 REN (0.47) CPB2DPP7
SCHEMBL8729043 0.90 CPB2 (0.46) CPB2DPP7MEN1KMT2AGHSR
SCHEMBL29381549 0.90 CPB2 (0.46) CPB2DPP7MEN1KMT2AGHSR
SCHEMBL23303426 0.89 MEN1 (0.48) CPB2DPP7MEN1KMT2AGHSR
SCHEMBL23303428 0.89 MEN1 (0.48) CPB2DPP7MEN1KMT2AGHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115403653-B D (+) -beta- (3, 4-dihydroxyphenyl) -lactoyl-Pro-Ala-Lys, synthesis and application thereof 首都医科大学 2024-08-06 — — CN claimed
EP-4306534-A1 MULTIFUNCTIONAL POLYPEPTIDE AND APPLICATION THEREOF IN FIELD OF MEDICINES Wuhan Innerse Pharmaceutical Inc. (CN) 2024-01-17 — — EP claimed
US-20230312644-A1 COMPOUNDS HAVING TRIPLE ACTIVITIES OF THROMBOLYSIS, ANTITHROMBOTIC AND RADICAL SCAVENGING SHANGHAI LUMOSA THERAPEUTICS CO LTD (CN) 2023-10-05 — — US claimed
CN-112175041-B Ethyl QRPAK modified bis-carbolino piperazine diketone and preparation, activity and application thereof 首都医科大学(CN) 2023-01-13 — — CN claimed
CN-115403653-A D (+) -beta- (3, 4-dihydroxyphenyl) -lactyl-Pro-Ala-Lys, synthesis and application thereof 首都医科大学 2022-11-29 — — CN claimed
WO-2022188878-A1 MULTIFUNCTIONAL POLYPEPTIDE AND APPLICATION THEREOF IN FIELD OF MEDICINES 武汉英纳氏药业有限公司 2022-09-15 — — WO claimed
CN-112094318-B Ethyl RPAK modified bis-carbolino-piperazinediones, preparation, activity and use thereof 首都医科大学 2022-09-02 — — CN claimed
CN-110577574-B 1S-methyl-beta-tetrahydrocarboline acyl-K (PAK) -RGDV, and synthesis, activity and application thereof 首都医科大学 2022-08-09 — — CN claimed
CN-112010936-B Ethyl GRPAK modified bis-carbolino piperazine diketone and preparation, activity and application thereof 首都医科大学 2022-04-22 — — CN claimed
CN-111995661-B Ethyl ARPAK modified bis-carbolino-piperazinediones, preparation, activity and application thereof 首都医科大学 2022-04-22 — — CN claimed
CN-112010928-B Ethyl PAK modified bis-carbolino-piperazinedione, preparation, activity and application thereof 首都医科大学 2022-04-22 — — CN claimed
EP-4313104-B1 DC009 FOR TREATING ACUTE ISCHEMIC STROKE LUMOSA THERAPEUTICS CO LTD (TW) 2026-05-13 — — EP disclosed
EP-4516288-A3 PHARMACEUTICAL COMPOSITION COMPRISING THROMBOLYTIC PEPTIDE-TETRAHYDROISOQUINOLINE CONJUGATE Lumosa Therapeutics Co., Ltd. (TW) 2025-06-18 — — EP disclosed
US-20250186534-A1 PHARMACEUTICAL COMPOSITION COMPRISING THROMBOLYTIC PEPTIDE-TETRAHYDROISOQUINOLINE CONJUGATE LUMOSA THERAPEUTICS CO., LTD (TW) 2025-06-12 — — US disclosed
US-20250186534-A1 PHARMACEUTICAL COMPOSITION COMPRISING THROMBOLYTIC PEPTIDE-TETRAHYDROISOQUINOLINE CONJUGATE LUMOSA THERAPEUTICS CO., LTD (TW) 2025-06-12 — — US disclosed
US-11338008-B2 Pharmaceutical composition comprising thrombolytic peptide-tetrahydroisoquinoline conjugate LUMOSA THERAPEUTICS CO., LTD (TW) 2022-05-24 — — US disclosed
CN-112010936-B Ethyl GRPAK modified bis-carbolino piperazine diketone and preparation, activity and application thereof 首都医科大学 2022-04-22 — — CN disclosed
CN-111995661-B Ethyl ARPAK modified bis-carbolino-piperazinediones, preparation, activity and application thereof 首都医科大学 2022-04-22 — — CN disclosed
CN-112010928-B Ethyl PAK modified bis-carbolino-piperazinedione, preparation, activity and application thereof 首都医科大学 2022-04-22 — — CN disclosed
CN-112010928-B Ethyl PAK modified bis-carbolino-piperazinedione, preparation, activity and application thereof 首都医科大学 2022-04-22 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250186534-A1 PHARMACEUTICAL COMPOSITION COMPRISING THROMBOLYTIC PEPTIDE-TETRAHYDROISOQUINOLINE CONJUGATE PCSK9, SERPINC1, DDOST CPB2 78/4885DPP7 269/4885MEN1 308/4885
US-11338008-B2 Pharmaceutical composition comprising thrombolytic peptide-tetrahydroisoquinoline conjugate PCSK9, SERPINC1, DDOST CPB2 78/4885DPP7 269/4885MEN1 308/4885
US-20230312644-A1 COMPOUNDS HAVING TRIPLE ACTIVITIES OF THROMBOLYSIS, ANTITHROMBOTIC AND RADICAL SCAVENGING SERPINC1, PLAT, F2 CPB2 397/4885DPP7 2122/4885MEN1 1860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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