SCHEMBL29535299

SCHEMBL29535299

O=S(=O)(O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1OS(=O)(=O)O

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 1/20 0.40
▸ LGALS3 P17931 1/20 0.40
▸ CA12 O43570 6/20 0.38
▸ CA1 P00915 6/20 0.38
▸ CA2 P00918 6/20 0.38
▸ CA9 Q16790 6/20 0.38
▸ KDM4E B2RXH2 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ CYP2D6 P10635 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ LGALS8 O00214 2/20 0.33
▸ SLC2A1 P11166 1/20 0.33
▸ F10 P00742 2/20 0.33
▸ HK2 P52789 3/20 0.33
▸ HK1 P19367 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16728933 1.00 MAPK1 (0.40) MAPK1LGALS3CA12CA1CA2
SCHEMBL29535657 0.90 LGALS3 (0.36) MAPK1LGALS3CA12CA1CA2
SCHEMBL29535345 0.88 LGALS3 (0.38) MAPK1LGALS3CA12CA1CA2
SCHEMBL29534894 0.86 F10 (0.43) LGALS3CA2F10
SCHEMBL16729068 0.86 LGALS3 (0.36) MAPK1LGALS3CA12CA1CA2
SCHEMBL7121030 0.83 LGALS8 (0.47) LGALS3CA12CA1CA2CA9
SCHEMBL7121026 0.83 LGALS8 (0.47) LGALS3CA12CA1CA2CA9
SCHEMBL741519 0.82 SLC2A1 (0.42) MAPK1LGALS3CA12CA1CA2
SCHEMBL5318200 0.82 SLC2A1 (0.42) MAPK1LGALS3CA12CA1CA2
SCHEMBL150778 0.82 SLC2A1 (0.42) MAPK1LGALS3CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116622006-B Short acting heparin-based anticoagulant compounds and methods 北卡罗来纳大学查珀尔希尔分校 2025-05-30 — — CN claimed
CN-110446511-B Short acting heparin-based anticoagulant compounds and methods 北卡罗来纳大学查珀尔希尔分校 2024-04-02 — — CN claimed
US-20240066048-A1 SHORT-ACTING HEPARIN-BASED ANTICOAGULANT COMPOUNDS AND METHODS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2024-02-29 — — US claimed
US-11903963-B2 Short-acting heparin-based anticoagulant compounds and methods THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2024-02-20 — — US claimed
CN-116622006-A Short acting heparin-based anticoagulant compounds and methods 北卡罗来纳大学查珀尔希尔分校 2023-08-22 — — CN claimed
US-20220404379-A1 SEQUENCING METHOD, SYSTEM AND KIT OF LOW MOLECULAR WEIGHT HEPARIN OLIGOSACCHARIDES SHANDONG UNIVERSITY (CN) 2022-12-22 — — US claimed
WO-2026041790-A1 DI(DISPIRODIAZATRIPIPERAZINE)-TRIAZINE DERIVATIVES AND THEIR USE FOR TREATMENT OR PREVENTION OF VIRAL INFECTIONS Charité - Universitätsmedizin Berlin Körperschaft des öffentlichen Rechts (DE) 2026-02-26 — — WO disclosed
US-12539311-B2 Short-acting heparin-based anticoagulant compounds and methods THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2026-02-03 — — US disclosed
CN-116622006-B Short acting heparin-based anticoagulant compounds and methods 北卡罗来纳大学查珀尔希尔分校 2025-05-30 — — CN disclosed
US-20240366853-A1 METHOD FOR MODULATING ENDOTHELIAL GLYCOCALYX STRUCTURE EXTHERA MEDICAL CORPORATION (US) 2024-11-07 — — US disclosed
US-12090261-B2 Method for modulating endothelial glycocalyx structure EXTHERA MEDICAL CORPORATION (US) 2024-09-17 — — US disclosed
EP-4426750-A2 METHODS FOR THE CHEMOENZYMATIC SYNTHESIS OF LOW MOLECULAR WEIGHT HEPARIN FROM LOW MOLECULAR WEIGHT HEPAROSAN Rensselaer Polytechnic Institute (US) 2024-09-11 — — EP disclosed
CN-110446511-B Short acting heparin-based anticoagulant compounds and methods 北卡罗来纳大学查珀尔希尔分校 2024-04-02 — — CN disclosed
US-20220404379-A1 SEQUENCING METHOD, SYSTEM AND KIT OF LOW MOLECULAR WEIGHT HEPARIN OLIGOSACCHARIDES SHANDONG UNIVERSITY (CN) 2022-12-22 — — US disclosed
CN-113393904-B Method and system for detecting low-molecular heparin sugar chain sequence and sequencing kit 山东大学 2022-10-18 — — CN disclosed
CN-114814010-A Two-dimensional liquid phase-mass spectrum combined method for low molecular weight heparin mass analysis 苏州大学 2022-07-29 — — CN disclosed
WO-2022124944-A1 DI(DIAZONIADISPIRO[5.2.5.2]HEXADECAN)-5-NITROPYRIMIDINES FOR THE TREATMENT OF CORONAVIRAL INFECTIONS FEDERAL RESEARCH CENTRE “FUNDAMENTALS OF BIOTECHNOLOGY” OF THE RUSSIAN ACADEMY OF SCIENCES (RU) 2022-06-16 — — WO disclosed
CN-114591451-A Partial anticoagulant heparin derivative and preparation method and application thereof 苏州大学 2022-06-07 — — CN disclosed
EP-3011043-B1 REVERSIBLE HEPARIN MOLECULES UNIV NORTH CAROLINA CHAPEL HILL (US) 2022-05-11 — — EP disclosed
EP-3969014-A1 METHOD FOR MODULATING ENDOTHELIAL GLYCOCALYX STRUCTURE ExThera Medical Corporation (US) 2022-03-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11903963-B2 Short-acting heparin-based anticoagulant compounds and methods HPSE, STS, SULT1A1 MAPK1 2401/4885LGALS3 3457/4885CA12 376/4885
US-20240066048-A1 SHORT-ACTING HEPARIN-BASED ANTICOAGULANT COMPOUNDS AND METHODS HPSE, STS, SULT1A1 MAPK1 2401/4885LGALS3 3457/4885CA12 376/4885
US-12539311-B2 Short-acting heparin-based anticoagulant compounds and methods STS, TPST2, HPSE MAPK1 2281/4885LGALS3 2892/4885CA12 160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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