Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147944 | 0.79 | METAP2 (0.42) | — | |
| SCHEMBL14131007 | 0.78 | NOS2 (0.44) | — | |
| SCHEMBL13026656 | 0.78 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL9275163 | 0.77 | ESR1 (0.58) | — | |
| SCHEMBL27497187 | 0.76 | LTA4H (0.55) | — | |
| SCHEMBL22968991 | 0.76 | NTRK1 (0.42) | — | |
| SCHEMBL31135323 | 0.76 | CYP19A1 (0.49) | — | |
| SCHEMBL2872833 | 0.75 | CALM1 (0.52) | — | |
| Hydrochloric Acid SCHEMBL23068534 | 0.74 | NTRK1 (0.41) | — | |
| Hydrochloric Acid SCHEMBL23068338 | 0.73 | CALM1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976053-A1 | COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISEASE | Avolynt (US) | 2022-04-06 | — | — | EP | disclosed |