Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3684293 | 0.91 | THRB (0.39) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL13801023 | 0.76 | POLB (0.43) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL28552216 | 0.76 | POLB (0.44) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL7872447 | 0.73 | TDP1 (0.44) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL15188011 | 0.73 | CYP2C19 (0.41) | HTTTDP1THRBCYP2C19HIF1A | |
| Hydrochloric Acid SCHEMBL27613881 | 0.73 | POLB (0.40) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL115658 | 0.72 | KIF11 (0.46) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL15224723 | 0.72 | ALDH1A1 (0.38) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL8850852 | 0.71 | HIF1A (0.49) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL15168704 | 0.71 | CYP2C19 (0.39) | TDP1CYP2C19HIF1ACHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986943-A1 | ANAEROBICALLY CURABLE COMPOSITIONS | Henkel IP & Holding GmbH (DE) | 2022-04-27 | — | — | EP | disclosed |
| US-20220089920-A1 | Anaerobically Curable Compositions | HENKEL AG & CO. KGAA (DE) | 2022-03-24 | — | — | US | disclosed |