Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 6/20 | 0.61 |
| ▸ | AHCY | P23526 | 3/20 | 0.52 |
| ▸ | PRKACA | P17612 | 3/20 | 0.48 |
| ▸ | NNMT | P40261 | 1/20 | 0.48 |
| ▸ | WDR5 | P61964 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RBBP5 | Q15291 | 3/20 | 0.45 |
| ▸ | DPY30 | Q9C005 | 3/20 | 0.45 |
| ▸ | ASH2L | Q9UBL3 | 3/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30744243 | 0.90 | DOT1L (0.49) | DOT1LAHCYPRKACANNMTPRMT1 | |
| SCHEMBL16578293 | 0.82 | DOT1L (0.68) | DOT1LAHCYPRKACANNMTWDR5 | |
| SCHEMBL10887920 | 0.75 | DOT1L (0.62) | DOT1LAHCYPRKACA | |
| SCHEMBL30744295 | 0.74 | KLK7 (0.46) | DOT1LAHCYPRKACA | |
| SCHEMBL5944004 | 0.74 | DOT1L (0.61) | DOT1LAHCYPRKACA | |
| SCHEMBL23056483 | 0.74 | DOT1L (0.51) | DOT1LPRKACA | |
| SCHEMBL16574770 | 0.73 | DOT1L (0.60) | DOT1LAHCYPRKACA | |
| SCHEMBL22799204 | 0.72 | AHCY (0.55) | AHCY | |
| SCHEMBL30744302 | 0.72 | AHCY (0.45) | DOT1LAHCYPRKACA | |
| SCHEMBL30744251 | 0.72 | ADORA3 (0.53) | DOT1LAHCYKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974563-A1 | CYCLIC PEPTIDES | Chugai Seiyaku Kabushiki Kaisha (JP) | 2022-03-30 | — | — | EP | disclosed |