SCHEMBL29540375

SCHEMBL29540375

N[C@@H](CCC(=O)O)C(=O)C(=O)OCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 6/20 0.52
HTT P42858 1/20 0.49
SLC15A1 P46059 2/20 0.46
ALDH1A1 P00352 3/20 0.45
SLC1A3 P43003 1/20 0.44
SLC1A1 P43005 1/20 0.44
CPA3 P15088 1/20 0.44
FOLH1 Q04609 2/20 0.44
MAPK1 P28482 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A3 Q01959 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20880748 0.90 ALDH1A1 (0.44) LTA4HHTTSLC15A1ALDH1A1SLC1A3
SCHEMBL23937606 0.90 ALDH1A1 (0.44) LTA4HHTTSLC15A1ALDH1A1SLC1A3
SCHEMBL31668437 0.90 LTA4H (0.44) LTA4HHTTSLC15A1ALDH1A1SLC1A3
SCHEMBL23937492 0.90 ALDH1A1 (0.44) LTA4HHTTSLC15A1ALDH1A1SLC1A3
SCHEMBL30415091 0.86 ALDH1A1 (0.46) LTA4HSLC15A1ALDH1A1SLC1A3SLC1A1
SCHEMBL24328246 0.86 SLC1A3 (0.41) LTA4HHTTSLC15A1ALDH1A1SLC1A3
SCHEMBL561573 0.86 LTA4H (0.56) LTA4HHTTSLC15A1ALDH1A1SLC1A3
SCHEMBL124387 0.86 LTA4H (0.56) LTA4HHTTSLC15A1ALDH1A1SLC1A3
SCHEMBL21232385 0.86 LTA4H (0.56) LTA4HHTTSLC15A1ALDH1A1SLC1A3
SCHEMBL28192478 0.86 LTA4H (0.56) LTA4HHTTSLC15A1ALDH1A1SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250289842-A1 Processes for Making NAG-25, a Carbohydrate Targeting Moiety, and its Intermediates AMGEN INC. 2025-09-18 US claimed
EP-4519278-A1 PROCESSES FOR MAKING NAG-25, A CARBOHYDRATE TARGETING MOIETY, AND ITS INTERMEDIATES Amgen Inc. (US) 2025-03-12 EP claimed
CN-119562958-A Methods for preparing NAG-25 carbohydrate targeting moieties and intermediates thereof 安进公司 2025-03-04 CN claimed
WO-2023215306-A1 PROCESSES FOR MAKING NAG-25, A CARBOHYDRATE TARGETING MOIETY, AND ITS INTERMEDIATES AMGEN INC. (US) 2023-11-09 WO claimed
US-20260070946-A1 TYR PEPTIDE COMPOSITIONS AND METHODS FOR USE UNIV MIAMI (US) 2026-03-12 US disclosed
US-12559801-B2 Compositions and methods for treating breast cancer THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2026-02-24 US disclosed
US-20250289842-A1 Processes for Making NAG-25, a Carbohydrate Targeting Moiety, and its Intermediates AMGEN INC. 2025-09-18 US disclosed
CN-110998328-B Diagnosis and treatment of cancer 拉布诊断公司 2025-05-02 CN disclosed
WO-2025090760-A1 ANTIBODIES SPECIFIC TO SCUBE3 AND METHODS OF USE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-05-01 WO disclosed
US-12274697-B2 Compositions and methods for treating EZH2-mediated cancer ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2025-04-15 US disclosed
EP-4519278-A1 PROCESSES FOR MAKING NAG-25, A CARBOHYDRATE TARGETING MOIETY, AND ITS INTERMEDIATES Amgen Inc. (US) 2025-03-12 EP disclosed
CN-119562958-A Methods for preparing NAG-25 carbohydrate targeting moieties and intermediates thereof 安进公司 2025-03-04 CN disclosed
US-11572630-B2 Method and apparatus for water electrolysis, and method for determining drive potential of water electrolysis RIKEN (JP) 2023-02-07 US disclosed
US-11510920-B2 Compositions and methods for treating EZH2-mediated cancer ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2022-11-29 US disclosed
US-11506668-B2 Diagnosis and treatment of cancer RAB DIAGNOSTICS AS (NO) 2022-11-22 US disclosed
US-20220259674-A1 COMPOSITIONS AND METHODS FOR TREATING BREAST CANCER FRED HUTCHINSON CANCER CENTER 2022-08-18 US disclosed
US-20220211864-A1 ANTIBODY-DRUG CONJUGATES WITH IMMUNE-MEDIATED THERAPY AGENTS MEDIMMUNE LIMITED (GB) 2022-07-07 US disclosed
EP-3998275-A1 RECOMBINANT PEPTIDES THAT BIND TO A TUMOUR-SPECIFIC ANTIBODY FOR BREAST CANCER AND USE Universidade Federal de Uberlândia (BR) 2022-05-18 EP disclosed
US-11306326-B2 Biologically active synthetic nanoparticle constructs and methods of use thereof RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2022-04-19 US disclosed
CN-114040996-A Method and apparatus for electrolyzing water, and method for determining driving potential of electrolyzed water 国立研究开发法人理化学研究所 2022-02-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289842-A1 Processes for Making NAG-25, a Carbohydrate Targeting Moiety, and its Intermediates ENGASE, MAN2B2, GALNT2 LTA4H 3651/4885HTT 4087/4885SLC15A1 1474/4885
US-12274697-B2 Compositions and methods for treating EZH2-mediated cancer EZH2, EZH1, EED LTA4H 3140/4885HTT 2868/4885SLC15A1 4788/4885
US-11510920-B2 Compositions and methods for treating EZH2-mediated cancer EZH2, EZH1, EED LTA4H 3140/4885HTT 2868/4885SLC15A1 4788/4885
US-20220211864-A1 ANTIBODY-DRUG CONJUGATES WITH IMMUNE-MEDIATED THERAPY AGENTS IGSF11, MCTS1, PAICS LTA4H 2400/4885HTT 1994/4885SLC15A1 738/4885
US-12559801-B2 Compositions and methods for treating breast cancer HSPA4L, EPB41L2, MELK LTA4H 2749/4885HTT 4747/4885SLC15A1 1559/4885
US-20260070946-A1 TYR PEPTIDE COMPOSITIONS AND METHODS FOR USE XPNPEP1, PRAP1, YBX1 LTA4H 4130/4885HTT 2773/4885SLC15A1 2078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.