Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.31 |
| ▸ | CNR2 | P34972 | 3/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30393120 | 0.88 | NPC1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL30531000 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL30531007 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL30531010 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL30530999 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL29540992 | 0.81 | L3MBTL1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL29540993 | 0.81 | L3MBTL1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL21797755 | 0.81 | L3MBTL1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL29541165 | 0.77 | NPC1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL29540788 | 0.74 | KIF11 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110494458-B | Alumoxane-activated metallocene catalysts | 博里利斯股份公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-110337455-B | Catalyst system for the production of polyethylene copolymers in a high temperature solution polymerization process | 博里利斯股份公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-110234665-B | Catalyst system for preparing polyethylene copolymers in high temperature solution polymerization process | 博里利斯股份公司 | 2022-05-24 | — | — | CN | disclosed |