Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29540993 | 1.00 | L3MBTL1 (0.33) | L3MBTL1NPC1ALDH1A1CASP3RAB9A | |
| Hydrochloric Acid SCHEMBL29540992 | 1.00 | L3MBTL1 (0.33) | L3MBTL1NPC1ALDH1A1CASP3RAB9A | |
| Hydrochloric Acid SCHEMBL29541165 | 0.86 | NPC1 (0.33) | L3MBTL1NPC1ALDH1A1CASP3RAB9A | |
| Hydrochloric Acid SCHEMBL19813107 | 0.84 | NR1H2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL29540788 | 0.83 | KIF11 (0.32) | ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL29541614 | 0.83 | KIF11 (0.32) | — | |
| Hydrochloric Acid SCHEMBL29540980 | 0.82 | ALDH1A1 (0.33) | ALDH1A1RAB9APLA2G1BATG4B | |
| Hydrochloric Acid SCHEMBL30393120 | 0.81 | NPC1 (0.32) | NPC1CASP3RAB9ASENP8SENP7 | |
| Hydrochloric Acid SCHEMBL30530999 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL29540795 | 0.81 | CES2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630658-B2 | Low crystallinity ethylene-vinylcyclohexane copolymers | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2026-05-19 | — | — | US | disclosed |
| US-12209176-B2 | Ethylene-cyclic mono olefin copolymerizations | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2025-01-28 | — | — | US | disclosed |
| US-20240052147-A1 | ETHYLENE-CYCLIC MONO OLEFIN COPOLYMERIZATIONS | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2024-02-15 | — | — | US | disclosed |
| US-20240002561-A1 | LOW CRYSTALLINITY ETHYLENE-VINYLCYCLOHEXANE COPOLYMERS | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2024-01-04 | — | — | US | disclosed |
| US-20230416429-A1 | HIGH CRYSTALLINITY ETHYLENE-VINYLCYCLOHEXANE COPOLYMERS | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2023-12-28 | — | — | US | disclosed |
| US-11827775-B2 | Ethylene-cyclic mono olefin copolymerizations | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2023-11-28 | — | — | US | disclosed |
| EP-3601384-B1 | ALUMINOXANE-ACTIVATED METALLOCENE CATALYSTS | BOREALIS AG (AT) | 2023-05-03 | — | — | EP | disclosed |
| EP-3555148-B1 | CATALYST SYSTEM FOR PRODUCING POLYETHYLENE COPOLYMERS IN A HIGH TEMPERATURE SOLUTION POLYMERIZATION PROCESS | BOREALIS AG (AT) | 2023-04-05 | — | — | EP | disclosed |
| US-11560440-B2 | Aluminoxane-activated metallocene catalysts | BOREALIS AG (AT) | 2023-01-24 | — | — | US | disclosed |
| WO-2022123414-A1 | LOW CRYSTALLINITY ETHYLENE-VINYLCYCLOHEXANE COPOLYMERS | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2022-06-16 | — | — | WO | disclosed |
| WO-2022123413-A1 | HIGH CRYSTALLINITY ETHYLENE-VINYLCYCLOHEXANE COPOLYMERS | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2022-06-16 | — | — | WO | disclosed |
| US-20220185923-A1 | CATALYST SYSTEM | BOREALIS AG (AT) | 2022-06-16 | — | — | US | disclosed |
| US-20220119628-A1 | ETHYLENE-CYCLIC MONO OLEFIN COPOLYMERIZATIONS | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2022-04-21 | — | — | US | disclosed |
| US-11279781-B2 | Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process | BOREALIS AG (AT) | 2022-03-22 | — | — | US | disclosed |
| EP-3953403-A1 | CATALYST SYSTEM | Borealis AG (AT) | 2022-02-16 | — | — | EP | disclosed |
| US-20210095057-A1 | ALUMINOXANE-ACTIVATED METALLOCENE CATALYSTS | BOREALIS AG (AT) | 2021-04-01 | — | — | US | disclosed |
| WO-2020208128-A1 | CATALYST SYSTEM | BOREALIS AG (AT) | 2020-10-15 | — | — | WO | disclosed |
| WO-2020079552-A1 | ETHYLENE-CYCLIC MONO OLEFIN COPOLYMERIZATIONS | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2020-04-23 | — | — | WO | disclosed |
| US-20200079887-A1 | CATALYST SYSTEM FOR PRODUCING POLYETHYLENE COPOLYMERS IN A HIGH TEMPERATURE SOLUTION POLYMERIZATION PROCESS | BOREALIS AG (AT) | 2020-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11279781-B2 | Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process | OPRM1, SIGMAR1, AP2S1 | L3MBTL1 1892/4885NPC1 2435/4885ALDH1A1 4096/4885 |
| US-20220185923-A1 | CATALYST SYSTEM | CPNE4, INF2, CAD | L3MBTL1 2754/4885NPC1 2085/4885ALDH1A1 2581/4885 |
| US-12630658-B2 | Low crystallinity ethylene-vinylcyclohexane copolymers | HVCN1, H1-0, SUV39H1 | L3MBTL1 3222/4885NPC1 3029/4885ALDH1A1 922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.